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ProteomicsIdentification of sialyl Lewisa/x-modified surface proteins in Multiple Myeloma cells by LC-MS
The project aims at identifying surface proteins that are modified by the tetrasaccharide sialyl Lewisa/x and therefore serve as selectin ligands in Multiple Myeloma. To that end, we have performed an immunoprecipitation using the Heca452 antibody (which recognizes sialyl Lewisa/x-related structures...
ORGANISM(S): Homo sapiens (Human) 
2024-01-23 | PXD046178 | Pride
Mulriple myeloma Sialyl lewis a/x Selectin ligands 
UnknownDynamic biochemical tissue analysis detects functional L-selectin ligands on colon cancer tissues.
Not available
S-EPMC5345883 | biostudies-literature
TranscriptomicsLymphoid Priming in Human Bone Marrow Begins Prior to CD10 Expression with Up-Regulation of L-selectin
Studies of adult human hematopoiesis have until now relied on the expression of CD10 to define lymphoid commitment. We report a novel lymphoid-primed population in human bone marrow that is generated from hematopoietic stem cells (HSC) prior to the onset of CD10 expression and B cell commitment, and...
ORGANISM(S): Homo sapiens 
2012-08-14 | E-GEOD-35685 | biostudies-arrayexpress
UnknownDynamic biochemical tissue analysis detects functional selectin ligands on human cancer tissues.
Not available
S-EPMC6560120 | biostudies-literature
UnknownE-selectin ligands recognised by HECA452 induce drug resistance in myeloma, which is overcome by the E-selectin antagonist, GMI-1271.
Not available
S-EPMC5729350 | biostudies-literature
UnknownStaining of E-selectin ligands on paraffin-embedded sections of tumor tissue.
Not available
S-EPMC5930952 | biostudies-literature
UnknownP-selectin is a host receptor for Plasmodium MSP7 ligands.
Not available
S-EPMC4478713 | biostudies-literature
ProteomicsO-linked glicoproteomics of gastric cancer cell lines OCUM-1, N87 and KATO-III
Gastric cancer (GC) is the third leading cause of cancer-related death worldwide, continuously requiring innovative target therapies. The sialyl-lewis A (SLeA) antigen offers tremendous potential for precise cancer targeting. This glycan is rarely expressed by healthy tissues and blood cells but is ...
ORGANISM(S): Homo sapiens (Human) 
2020-05-11 | PXD016968 | Pride
Human Glycoproteomics Sialyl-lewis a Gastric cancer Cell lines Lc-ms/ms 
UnknownEndothelial L-selectin ligands are likely to recruit lymphocytes into rejecting human heart transplants.
Not available
S-EPMC1867005 | biostudies-literature
UnknownGlycoengineering of E-Selectin Ligands by Intracellular versus Extracellular Fucosylation Differentially Affects Osteotropism of Human Mesenchymal Stem Cells.
Not available
S-EPMC5064874 | biostudies-literature
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