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TranscriptomicsGene regulation in ki-ras transfected murine fibroblasts
Ki-ras gene mutations are involved in the carcinogenesis of acute myeloid leukemia, melanoma and different carcinomas. In order to define potential mutation-specific therapeutic targets, expression profiling analyses were performed using stable transfected NIH3T3 cells carrying different ki-ras gene...
ORGANISM(S): Mus musculus 
2010-05-25 | E-GEOD-8372 | biostudies-arrayexpress
UnknownA gene expression signature associated with B cells predicts benefit from immune checkpoint blockade in lung adenocarcinoma.
Not available
S-EPMC7808386 | biostudies-literature
UnknownDynamic cardiovascular risk assessment in elderly people. The role of repeated N-terminal pro-B-type natriuretic peptide testing.
Not available
S-EPMC2840257 | biostudies-literature
TranscriptomicsIdentification and validation of novel ERBB2 (HER2, NEU) targets including genes
V-erb-b2 erythroblastic leukemia viral oncogene homolog 2 (ERBB2; synonyms HER2, NEU) encodes a transmembrane glycoprotein with tyrosine kinase-specific activity that acts as a major switch in different signal-transduction processes. ERBB2 amplification and overexpression have been found in a number...
ORGANISM(S): Mus musculus 
2010-06-25 | E-GEOD-16445 | biostudies-arrayexpress
UnknownRole of HLA-G in Viral Infections.
Not available
S-EPMC8882596 | biostudies-literature
TranscriptomicsGene regulation in Erbb2 transfected NIH3T3 cells using tet-off system
V-erb-b2 erythroblastic leukemia viral oncogene homolog 2 (ERBB2; synonyms HER2, NEU) encodes a transmembrane glycoprotein with tyrosine kinase-specific activity that acts as a major switch in different signal-transduction processes. ERBB2 amplification and overexpression have been found in a number...
ORGANISM(S): Mus musculus 
2009-09-01 | E-GEOD-8373 | biostudies-arrayexpress
TranscriptomicsExpression profiling analysis of thymus and brain from EMP3 mutant mice
Background: Epithelial membrane protein 3 (EMP3) was previously reported to be involved in immunological reactions and in tumor as potential suppressor, as well as a candidate gene for cardiac dystrophic calcification (DCC). Given its assumed role in different disorders, we aimed to generate and per...
ORGANISM(S): Mus musculus 
2011-01-01 | E-GEOD-19871 | biostudies-arrayexpress
TranscriptomicsGene regulation in Erbb2 transfected NIH3T3 cells after Azacytidine treatment
5-Azacytidine or 5-aza-2â??-deoxycytidine is a chemical analogue of the cytosine nucleoside used in DNA and RNA. Cells in the presence of 5-azacytidine incorporate it into DNA during replication and RNA during transcription. The incorporation of 5-azacytidine into DNA or RNA inhibits methyltransfera...
ORGANISM(S): Mus musculus 
2009-10-01 | E-GEOD-8374 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of Sunitinib-treated but not untreated short-term serum-free cultures predict treatment response of human high-grade gliomas in vitro
High-grade gliomas are amongst the most deadly human tumors. Treatment results are overall disappointing. Nevertheless, in several trials around 20% of patients respond to therapy. Diagnostic strategies to identify those patients that will ultimately profit from a specific targeted therapy are urgen...
ORGANISM(S): Homo sapiens 
2014-10-07 | E-GEOD-51305 | biostudies-arrayexpress
UnknownComprehensive flow cytometric reference intervals of leukocyte subsets from six study centers across Europe.
Not available
S-EPMC7670136 | biostudies-literature
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