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TranscriptomicsThe transcription factor Ahr1 links cell size control to amino acid metabolism in the opportunistic yeast Candida albicans
This work reports the role of the transcription factor Ahr1 in mediating cell size control in the pathogenic yeast Candida albicans. To investigate the role of Ahr1 at Start, we performed a transcriptional profiling by comparing the transcriptome of G1 phase cells of both WT and ahr1 mutant strains.
ORGANISM(S): Candida albicans 
2022-04-12 | E-MTAB-11615 | biostudies-arrayexpress
TranscriptomicsA toolbox for epitope-tagging and genome-wide location analysis in Candida albicans
Background : Candida albicans is a diploid pathogenic fungus not yet amenable to routine genetic investigations. Understanding aspects of the regulation of its biological functions and the assembly of its protein complexes would lead to further insight into the biology of this common disease-causing...
ORGANISM(S): Candida albicans 
2010-05-16 | E-GEOD-13427 | biostudies-arrayexpress
TranscriptomicsTranscriptional control of hypoxic hyphal growth in the fungal pathogen Candida albicans
So far, there is no known regulatory circuits that mediate filamentation of the pathogenic yeast Candida albicans exclusively in response to hypoxia. In this study, we performed a quantitative analysis of gene deletion mutants from different collections of protein kinases and transcriptional regulat...
ORGANISM(S): Candida albicans 
2021-08-18 | E-MTAB-10882 | biostudies-arrayexpress
ProteomicsManganese-modulated proteome and phospho-proteome of the opportunistic yeast Candida albicans
The ability of the opportunistic yeast Candida albicans to acquire and maintain homeostatic levels of manganese (Mn), particularly in the metal-limited host environment, is an important determinant of its fitness. Although significant focus has been given to mechanisms of iron and copper acquisition...
ORGANISM(S): Candida albicans (Yeast) 
2025-06-12 | PXD064206 | Pride
Candida albicans  metal homeostasis  manganese starvation  proteomic  phosphoproteome 
TranscriptomicsExperimental annotation of the human pathogen Candida albicans coding and noncoding transcribed regions using high resolution tiling arrays
Compared to other model organisms and despite the clinical relevance of the pathogenic yeast Candida albicans, no comprehensive analysis has been done to provide experimental support of its in silico-based genome annotation. Here we have undertaken a genome-wide experimental annotation to accurately...
ORGANISM(S): Candida albicans 
2010-07-07 | E-GEOD-22625 | biostudies-arrayexpress
TranscriptomicsPho85, Pcl1, and Hms1 Signaling Governs Candida albicans Morphogenesis Induced by Elevated Temperature or Hsp90 Compromise [mRNA]
The capacity to sense and transduce temperature signals pervades all aspects of biology, and temperature exerts powerful control over the development and virulence of diverse pathogens. In the leading fungal pathogen of humans, Candida albicans, temperature has a profound impact on morphogenesis, a ...
ORGANISM(S): Candida albicans 
2012-03-20 | E-GEOD-34255 | biostudies-arrayexpress
TranscriptomicsPho85, Pcl1, and Hms1 Signaling Governs Candida albicans Morphogenesis Induced by Elevated Temperature or Hsp90 Compromise [ChIP-chip]
The capacity to sense and transduce temperature signals pervades all aspects of biology, and temperature exerts powerful control over the development and virulence of diverse pathogens. In the leading fungal pathogen of humans, Candida albicans, temperature has a profound impact on morphogenesis, a ...
ORGANISM(S): Candida albicans 
2012-03-20 | E-GEOD-34938 | biostudies-arrayexpress
TranscriptomicsA functional portrait of Med7 and the Mediator complex in Candida albicans [ChIP-chip]
In this study, we have investigated Mediator function in the human fungal pathogen C. albicans. An initial screening of conditionally regulated Mediator subunits showed that the Med7 of C. albicans was not essential, in contrast to the situation noted for Saccharomyces cerevisiae. While loss of CaMe...
ORGANISM(S): Candida albicans 
2014-09-18 | E-GEOD-61518 | biostudies-arrayexpress
TranscriptomicsChIP-chip to investigate transcriptional control of hypoxic hyphal growth in the fungal pathogen Candida albicans
So far, there is no known regulatory circuits that mediate filamentation of the pathogenic yeast Candida albicans exclusively in response to hypoxia. In this study, we performed a quantitative analysis of gene deletion mutants from different collections of protein kinases and transcriptional regulat...
ORGANISM(S): Candida albicans 
2021-08-18 | E-MTAB-10883 | biostudies-arrayexpress
TranscriptomicsThe zinc cluster transcription factor Ahr1p directs Mcm1p regulation of Candida albicans adhesion
Biofilm development by Candida albicans requires cell adhesion for the initial establishment of the biofilm and the continued stability after hyphal development occurs; however, the regulation of the process has not been fully established. Using chromatin immunoprecipitation coupled to microarray an...
ORGANISM(S): Candida albicans 
2010-11-10 | E-GEOD-25174 | biostudies-arrayexpress
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