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ProteomicsSemaphorin 5A modulates focal adhesion pathway and lamellipodia formation in melanoma
Introduction Metastatic potential and rising incidence make cutaneous melanoma a major health concern worldwide. Although the therapies currently in use have proven effective, their use is limited by side effects arising and development of drug resistance. For this reason, re...
ORGANISM(S): Homo sapiens (Human) 
2025-12-01 | PXD065661 | Pride
Semaphorin 5a Melanoma Lamellipodia Focal adhesion 
GenomicsMicroarray analysis of lung cancer cells gene expression in overexpressing different semaphorin 5a domains
Microarray analysis of lung cancer cells gene expression in overexpressing different semaphorin 5a domains
PRJNA660000 | ENA
TranscriptomicsMicroarray analysis of lung cancer cells gene expression in overexpressing different semaphorin 5a domains
Semaphorin 5A (SEMA5A) is one member of semaphorin family, which was identified as an axon guidance molecule in nervous systems. In our previous studies, SEMA5A was identified as a prognostic biomarker for lung cancer in nonsmoking women and acted as a tumor suppressor gene in inhibiting the prolife...
ORGANISM(S): Homo sapiens 
2023-08-19 | GSE157062 | GEO
UnknownSemaphorin 5A suppresses ferroptosis through activation of PI3K-AKT-mTOR signaling in rheumatoid arthritis.
Not available
S-EPMC9283415 | biostudies-literature
UnknownThe association of semaphorin 5A with lymph node metastasis and adverse prognosis in cervical cancer.
Not available
S-EPMC6013961 | biostudies-literature
UnknownHelicobacter pylori promotes gastric cancer progression by upregulating semaphorin 5A expression via ERK/MMP9 signaling.
Not available
S-EPMC8424108 | biostudies-literature
UnknownPlexin-B3 is a functional receptor for semaphorin 5A.
Not available
S-EPMC1299100 | biostudies-literature
UnknownSemaphorin-5A maintains epithelial phenotype of malignant pancreatic cancer cells.
Not available
S-EPMC6303891 | biostudies-literature
UnknownStructure and function of Semaphorin-5A glycosaminoglycan interactions.
Not available
S-EPMC10978931 | biostudies-literature
UnknownSemaphorin 5A suppresses the proliferation and migration of lung adenocarcinoma cells.
Not available
S-EPMC6910195 | biostudies-literature
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