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UnknownProtective effect and the therapeutic index of indralin in juvenile rhesus monkeys.
Not available
S-EPMC4229912 | biostudies-literature
ProteomicsBoosting MS1-only proteomics with machine learning allows 2000 protein identifications in single-shot human proteome analyses using 5-minute HPLC gradients
Proteome-wide analyses rely on tandem mass spectrometry and extensive separation of proteolytic mixtures imposing considerable instrumental time consumption that is one of the main obstacles in a broader acceptance of proteomics in biomedical and clinical research. Recently, we presented a fast prot...
ORGANISM(S): Homo sapiens (Human) 
2021-03-18 | PXD023977 | Pride
Faims Fusion lumos Mass spectrometry Ms1-only Hela Protein identification 
ProteomicsDirectMS1: MS/MS-free identification of 1000 proteins of cellular proteomes in 5 minutes
Proteome characterization relies heavily on tandem mass spectrometry (MS/MS) and is thus associated with instrumentation complexity, lengthy analysis time, and limited duty-cycle. It was always tempting to implement approaches which do not require MS/MS, yet, they were constantly failing in achievin...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2020-02-27 | PXD015669 | Pride
Qexactive hf Mass spectrometry Yeast Ms1-only Hela Protein identification Dda 
ProteomicsRpn4- and Proteasome- Mediated Yeast Response to Ethanol Stress: a View from a Proteome
Distilled spirits production using S. cerevisiae requires understanding the mechanisms of yeast cell response to the alcohol stress. Reportedly, specific mutations in genes of the ubiquitin-proteasome system, e.g. RPN4, may result in strains exhibiting either hyper-resistance or increased sensitivit...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-04-22 | PXD014236 | Pride
S. cerevisiae Ethanol Cell stress Rpn4 Shotgun proteomics 
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