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MetabolomicsSequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID

The post-acute sequelae of COVID-19 (PASC), also known as long COVID, is often associated with debilitating symptoms and adverse multisystem consequences. We obtain plasma samples from 117 individuals during and 6 mth following their acute phase of infection to comprehensively profile and as...

2024-02-23 | MTBLS7337 | MetaboLights
MetabolomicsMetabolic-engineered probiotic-OMVs as nanovaccine mediating sequential immunomodulation for chronic bone infection immunotherapy

Chronic, drug-resistant bone infection caused by methicillin-resistant Staphylococcus aureus (MRSA) features an immunosuppressive niche enabling persistent infection and impaired bone healing. Specific treatment requires initial antibacterial immune activation against infection, followed by resha...

2026-03-19 | MTBLS14091 | MetaboLights
ProteomicsSalmon larvae proteomics - Sequential protein extraction as an efficient method for improved proteome coverage in larvae of Atlantic salmon (Salmo salar)
Application of a solubility-based sequential protein extraction method to improve proteome coverage in whole fish
ORGANISM(S): Salmo salar (Atlantic salmon) 
2016-06-13 | PXD003366 | Pride
Sequential extraction  differential solubility  whole-fish proteomics 
MetabolomicsSequential lipidomic, metabolomic, and proteomic analyses of serum, liver, and heart tissue specimens from peroxisomal biogenesis factor 11α knockout mice
Peroxisomes are versatile single membrane-enclosed cytoplasmic organelles, involved in reactive oxygen species (ROS) and lipid metabolism and diverse other metabolic processes. Peroxisomal disorders result from mutations in Pex genes-encoded proteins named peroxins (PEX proteins) and single peroxiso...
2022-02-02 | MTBLS1887 | MetaboLights
ProteomicsSurfactant and chaotropic agent assisted sequential extraction/on pellet digestion (SCAD) for enhanced proteomics
As a popular sample preparation approach, Filter-aided sample preparation (FASP) has been widely used in proteomic analysis. However, several limitations have been noted, including sample loss during filtration, repetitive centrifugation steps, and the possibility of breakage of filtration membrane....
ORGANISM(S): Homo sapiens (Human) 
2018-10-19 | PXD008967 | Pride
Urea Protein digestion Protein detection Protein extraction Peptide sequencing Lfq Scad Ibaq Fasp 
TranscriptomicsSequential changes at differentiation gene promoters as they become active in a stem cell lineage
Transcriptional silencing of terminal differentiation genes by the Polycomb group (PcG) machinery is emerging as a key feature of precursor cells in stem cell lineages. How, then, is this epigenetic silencing reversed for proper cellular differentiation? Here we investigate how the developmental pro...
ORGANISM(S): Drosophila melanogaster 
2011-07-14 | E-GEOD-28728 | biostudies-arrayexpress
UnknownRecovery and partial isolation of ⍺-mangostin from mangosteen pericarpsvia sequential extraction and precipitation.
Not available
S-EPMC11508469 | biostudies-literature
UnknownOptimization and assessment of a sequential extraction procedure for calcium carbonate rocks.
Not available
S-EPMC8364905 | biostudies-literature
UnknownFractions of arsenic and selenium in fly ash by ultrasound-assisted sequential extraction.
Not available
S-EPMC9050076 | biostudies-literature
Genomics
Sequential DNA extraction for soil microbiome study
PRJNA1327625 | ENA
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