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ProteomicsA Metabolite-bridged complex between SerRS and SIRT2 couples NAD+ metabolism to translation control
Cellular homeostasis requires tight coordination between metabolic and translational networks. Here we identify a direct molecular link between these processes through a cryo-EM structure of human cytosolic seryl-tRNA synthetase (SerRS) in complex with the NAD⁺-dependent deacetylase SIRT2. This inte...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD079339 | Pride
Serrs Nad+ metabolite Translational control Sirt2 Adp-ribose Oxidative stress 
GenomicsSerRS mediates translational readthrough of through engagement of the selenocysteine incorporation machinery
SerRS mediates translational readthrough of through engagement of the selenocysteine incorporation machinery
PRJNA851750 | ENA
OtherSerRS mediates translational readthrough of through engagement of the selenocysteine incorporation machinery
Translational readthrough of UGA stop codons by selenocysteine-specific tRNAs (tRNASec) provide the basis for selenoprotein biosynthesis. Seryl-tRNA synthetase (SerRS) charges tRNASec with serine, which is modified into selenocysteine, and delivered to the ribosome by a designated elongation factor ...
ORGANISM(S): Homo sapiens 
2026-06-11 | GSE206674 | GEO
UnknownTissue factor-specific ultra-bright SERRS nanostars for Raman detection of pulmonary micrometastases.
Not available
S-EPMC5438878 | biostudies-literature
UnknownChelator-Free Radiolabeling of SERRS Nanoparticles for Whole-Body PET and Intraoperative Raman Imaging.
Not available
S-EPMC5566106 | biostudies-literature
UnknownDetermination of Benzocaine in Pharmaceutical Formulations by Indirect SERRS Assay Combined with Azo Coupling.
Not available
S-EPMC9321682 | biostudies-literature
UnknownDetection and Identification of Estrogen Based on Surface-Enhanced Resonance Raman Scattering (SERRS).
Not available
S-EPMC6099535 | biostudies-literature
UnknownTargeting Angiogenesis by Blocking the ATM-SerRS-VEGFA Pathway for UV-Induced Skin Photodamage and Melanoma Growth.
Not available
S-EPMC6966470 | biostudies-literature
UnknownSerRS-tRNASec complex structures reveal mechanism of the first step in selenocysteine biosynthesis.
Not available
S-EPMC4666401 | biostudies-literature
UnknownOne-Shot SERRS Detection of Iron and Acidity in Aqueous Systems.
Not available
S-EPMC12862772 | biostudies-literature
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