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TranscriptomicsTranscriptome analysis of yeast methyltransferase mutants set5∆, set1∆ and set5∆set1∆
Purpose: Understand the synergistic relationship between the methyltransferases Set1 and Set5 in the regulation of gene expression. Methods: Total mRNA was obtained from two independent biological replicates each of wildtype (WT), set1∆, set5∆, SET5 Y402A and set1∆set5∆ S. cerevisiae strains. Libra...
ORGANISM(S): Saccharomyces cerevisiae 
2014-01-15 | E-GEOD-52086 | biostudies-arrayexpress
ProteomicsFunction of the MYND domain and C-terminal region in regulating the subcellular localization and catalytic activity of the SMYD family lysine methyltransferase Set5
SMYD lysine methyltransferases target histones and non-histone proteins for methylation and are critical regulators of muscle developmental and implicated in neoplastic transformation. They are characterized by a split catalytic SET domain and an intervening MYND zinc finger domain, as well as an ex...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-11-11 | PXD014756 | Pride
Methyltransferase Saccharomyces cerevisiae 
TranscriptomicsTranscriptome analysis of yeast methyltransferase mutants set5∆, set1∆ and set5∆set1∆
Purpose: Understand the synergistic relationship between the methyltransferases Set1 and Set5 in the regulation of gene expression. Methods: Total mRNA was obtained from two independent biological replicates each of wildtype (WT), set1∆, set5∆, SET5 Y402A and set1∆set5∆ S. cerevisiae strains. Librar...
ORGANISM(S): Saccharomyces cerevisiae 
2014-01-15 | GSE52086 | GEO
GenomicsSaccharomyces cerevisiae
Transcriptome analysis of yeast methyltransferase mutants set5∆, set1∆ and set5∆set1∆
PRJNA226646 | ENA
ProteomicsCharacterisation of protein methyltransferases Rkm1, Rkm4, Efm4, Efm7, Set5 and Hmt1 reveals extensive post-translational modification
Protein methylation is one of the major post-translational modifications (PTMs) in the cell. In Saccharomyces cerevisiae, over twenty protein methyltransferases (MTases) and their respective substrates have been identified. However, the way in which these MTases are modified, and potentially subject...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2017-12-18 | PXD006767 | Pride
Metyltransferases Post-translational modifications Rkm1 Hmt1 Efm7 Rkm4 Set5 Efm4 
UnknownSet5 and Set1 cooperate to repress gene expression at telomeres and retrotransposons.
Not available
S-EPMC4121362 | biostudies-literature
UnknownThe histone methyltransferases Set5 and Set1 have overlapping functions in gene silencing and telomere maintenance.
Not available
S-EPMC5330434 | biostudies-literature
UnknownMethylation of H4 lysines 5, 8 and 12 by yeast Set5 calibrates chromatin stress responses.
Not available
S-EPMC3334815 | biostudies-literature
UnknownModification of Phosphorylation Sites in the Yeast Lysine Methyltransferase Set5 Exerts Influences on the Mitogen-Activated Protein Kinase Hog1 under Prolonged Acetic Acid Stress.
Not available
S-EPMC10100857 | biostudies-literature
UnknownFunction of the MYND Domain and C-Terminal Region in Regulating the Subcellular Localization and Catalytic Activity of the SMYD Family Lysine Methyltransferase Set5.
Not available
S-EPMC6944473 | biostudies-literature
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