Sex as biological variable

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Unknown (396)
Transcriptomics (109)
Proteomics (101)
Genomics (65)
Metabolomics (22)
Methylation profiling (3)
Genomic (1)
Other (1)

Organisms

Schizophyllum commune H4-8 (98)
Mycobacterium tuberculosis SP7 (98)
Oryza sativa Japonica Group (98)
Eriocheir sinensis (98)
Candidatus Endoriftia persephonae (98)
Mycobacterium tuberculosis SP10 (98)
Mycobacterium tuberculosis SP13 (98)
Mycobacterium tuberculosis SP22 (98)
Enterobacter ludwigii (98)
Chlamydomonas reinhardtii (98)
Lama (98)
Homo sapiens (45)
Mus musculus (32)
Taeniopygia guttata (11)
Drosophila melanogaster (9)
Caenorhabditis elegans (4)
Rattus norvegicus (4)
Sturnus vulgaris (2)
Danio rerio (2)
Drosophila simulans (2)
Sus scrofa (2)
Loxia curvirostra (1)
Aspergillus flavus (1)
Macaca mulatta (1)
Phaeodactylum tricornutum (1)
Manduca sexta (1)
mouse gut metagenome (1)
Oncorhynchus mykiss (1)
Gallus gallus (1)
Arabidopsis thaliana (1)

Organisms

Mus musculus (21)
Homo sapiens (12)
Taeniopygia guttata (7)
Sus scrofa (2)
Drosophila simulans (1)
Drosophila melanogaster (1)
Oncorhynchus mykiss (1)

Repository

pride (98)
biostudies-arrayexpress (89)
ENA (56)
geo (33)
MetaboLights (22)
MassIVE (3)
dbGaP (1)

Tissue

Brain (18)
Blood plasma (9)
Tooth enamel (8)
Accessory sex gland (5)
Testis (5)
Kidney (5)
Heart (4)
Whole body (4)
Ovary (3)
Saliva (3)
Liver (3)
Blood cell (3)
Blood (3)
Cell culture (3)
Pheromone gland (2)
Tear (2)
Eye (2)
Salivary gland (2)
Cerebrospinal fluid (2)
Skin (2)
Bone marrow (2)
Spleen (2)
Erythrocyte (2)
Lung (2)
Primordial germ cell (1)
Choroid plexus epithelial cell (1)
Striatum (1)
Nectar (1)
Nectary (1)
Somatic cell (1)

Disease

Glaucoma (2)
Plasmodium falciparum malaria (2)
Cardiovascular system disease (2)
Alzheimer's disease (2)
Schizophrenia (2)
Disease free (2)
Normal (1)
Myelofibrosis (1)
Bacterial vaginosis (1)
Diabetic angiopathy (1)
Semantic dementia (1)
Hydrocephalus (1)
Fabry disease (1)
Aniridia (1)
Cerebrovascular disease (1)
Stroke (1)
Parkinson's disease (1)
Osteoarthritis (1)
COVID-19 (1)

Technology Type

Mass Spectrometry (98)
Shotgun proteomics (49)
Bottom-up proteomics (28)
Data-dependent acquisition (17)
Mass spectrometry (15)
SWATH MS (7)
Data-independent acquisition (6)
Affinity purification coupled with mass spectrometry proteomics (5)
SRM/MRM (4)
Gel-based experiment (4)
NMR spectroscopy (3)
Mass spectrometry assay (3)
HDMSE (3)
NMR spectroscopy assay (1)
Mass spectrometry imaging (1)
MSE (1)
All-ion fragmentation (1)
DiaPASEF (1)
Top-down proteomics (1)

Instrument Platform

Liquid Chromatography MS - positive - reverse phase (10)
Liquid Chromatography MS - negative - reverse phase (9)
Nuclear Magnetic Resonance (NMR) - (3)
Gas Chromatography MS - Positive (GC-MS (Positive)) (2)
Liquid Chromatography MS - negative - hilic (2)
-- (1)
Illumina Omni1-Quad Beadchip (1)
Illumina NovaSeq X (1)
NextSeq 2000 (1)
DNBSEQ-G400 (1)
Illumina MiSeq (1)
Illumina HiSeq 2500 (1)
Illumina NovaSeq 6000 (1)
Illumina HiSeq 2000 (1)
NextSeq 500 (1)
Orbitrap Fusion (1)
Orbitrap Exploris 480 (1)
Orbitrap Fusion Lumos (1)
Flow injection analysis MS – alternating (1)
Matrix-assisted laser desorption-ionisation imaging MS - (1)
Liquid Chromatography MS - Alternating (LC-MS (Alternating)) (1)
Liquid Chromatography MS - Negative (LC-MS (Negative)) (1)
Liquid Chromatography MS - Positive (LC-MS (Positive)) (1)
Nuclear Magnetic Resonance (NMR) (1)
Liquid Chromatography MS - negative - HILIC (1)
Liquid Chromatography MS - positive - HILIC (1)
Liquid Chromatography MS - positive - reverse-phase (1)
Liquid Chromatography MS - negative - reverse-phase (1)
Liquid Chromatography MS - positive - hilic (1)

Publication Date

2026 (34)
2024 (29)
2025 (26)
2012 (23)
2021 (14)
2016 (13)
2022 (13)
2015 (12)
2014 (12)
2023 (12)
2017 (10)
2019 (8)
2010 (8)
2020 (7)
2018 (7)
2011 (6)
2009 (4)
2008 (3)
2013 (2)
2007 (1)
2005 (1)

CHEBI ID

CHEBI:15891 (9)
CHEBI:16737 (9)
CHEBI:18050 (8)
CHEBI:16015 (8)
CHEBI:30915 (8)
CHEBI:17895 (8)
CHEBI:15756 (8)
CHEBI:18089 (8)
CHEBI:30769 (8)
CHEBI:16750 (7)
CHEBI:28875 (7)
CHEBI:17568 (7)
CHEBI:16259 (7)
CHEBI:16467 (7)
CHEBI:17203 (7)
CHEBI:48131 (7)
CHEBI:15971 (7)
CHEBI:16919 (7)
CHEBI:17295 (7)
CHEBI:17596 (7)
CHEBI:17368 (7)
CHEBI:16977 (6)
CHEBI:15741 (6)
CHEBI:41865 (6)
CHEBI:16196 (6)
CHEBI:27823 (6)
CHEBI:18176 (6)
CHEBI:7916 (6)
CHEBI:17750 (6)
CHEBI:73722 (6)

Metabolite Name

Creatinine (8)
L-Glutamine (7)
L-Valine (7)
L-Tyrosine (7)
Taurine (6)
Adenine (6)
Myristic acid (6)
Creatine (6)
L-Carnitine (6)
L-Leucine (6)
L-Alanine (5)
L-Lysine (5)
Kynurenic acid (5)
Choline (5)
Cytosine (5)
L-Tryptophan (5)
Dihydrouracil (5)
Uric acid (5)
Xanthine (5)
Uridine (5)
L-Isoleucine (5)
L-Phenylalanine (5)
Hypoxanthine (5)
LysoPC(16:1(9Z)/0:0) (4)
Tetradecanoylcarnitine (4)
Phenol (4)
Pyruvic acid (4)
1-(beta-D-Ribofuranosyl)-1,4-dihydronicotinamide (4)
Betaine (4)
Guanidoacetic acid (4)

First Public Date

2014 (14)
2026 (13)
2025 (13)
2024 (5)
2023 (5)
2022 (4)
2020 (1)
2018 (1)

Study type

Transcription profiling by array (51)
Methylation profiling by array (8)
Comparative genomic hybridization by array (6)
RNA-seq of coding RNA (5)
ChIP-chip by tiling array (4)
ChIP-seq (4)
RNA-seq of coding RNA from single cells (4)
Other (3)
Human - One-color microarray (1)
Animal - High-throughput sequencing (1)
MicroRNA profiling by array (1)
DNA-seq (1)

Release Date

2025 (66)
2022 (64)
2024 (59)
2021 (45)
2023 (45)
2020 (43)
2019 (30)
2012 (27)
2026 (14)
2016 (14)
2014 (14)
2018 (13)
2015 (12)
2010 (8)
2017 (7)
2011 (6)
2013 (5)
2008 (5)
2009 (4)
2007 (3)
2005 (1)

Lab affiliation

Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 (2)
Parasitology Laboratory, Institute of Natural Resources and Agrobiology (IRNASA, CSIC). Cordel de Merinas, 40-52, 37008 Salamanca, Spain. (2)
Shanghai Hoogen Biotechnology Co., Ltd. (2)
Department of Pharmacology and Neuroscience, The University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107, USA (1)
INRAE Val de Loire France (1)
Max F. Perutz Laboratories, University of Vienna, Austria (1)
Systems Biology of Pain,Division of Pharmacology & Toxicology, Department of Pharmaceutical Sciences, University of Vienna (1)
Cardiovascular Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana, 70112, USA (1)
Neurovascular Research Laboratory, Vall d’Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain. Stroke Research Program, Institute of Biomedicine of Seville, IBiS/Hospital Universitario Virgen del Rocío/CSIC/University of Seville & Department of Neurology, Hospital Universitario Virgen Macarena, Seville, Spain (1)
Professor School of Biological Sciences University of East Anglia Norwich UK (1)
DIVAS, Department of Veterinary Medicine and Animal Science (1)
School of Biosciences and Medicine, the University of Surrey, Guildford GU2 7XH, Surrey, UK Division of Immunology, Immunity to Infection and Respiratory Medicine, School of Biological Sciences, Manchester Institute of Biotechnology, Manchester Academic Health Sciences Centre, University of Manchester, Manchester M1 7DN, Greater Manchester, UK (1)
School of Life Science, East China Normal University, Shanghai 200241, China (1)
Department of Life Sciences, University of Modena and Reggio Emilia (1)
University of the Sunshine Coast, Maroochydore DC, Queensland 4557, Australia (1)
School of BioSciences, The University of Melbourne, Victoria, Australia (1)
Fundacion Instituto de Investigaciones Sanitarias de santiago de Compostela (1)
Johns Hopkins Bloomberg School of Public Health (1)
DIVAS (1)
Neil F. Inglis Moredun Proteomics Facility Moredun Research Institute Pentlands Science Park Bush Loan Penicuik Midlothian EH26 0PZ Tel +44 131 445 5111 (1)
Department of Biochemistry and Molecular Genetics University of Virginia School of Medicine (1)
Department of Neurology School of Medicine Oregon Health & Science University Portland, OR, USA (1)
Centre for Proteome Research, Institute of Integrative Biology, University of Liverpool, Liverpool, L69 7ZB, UK (1)
1Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands (1)
ProGenTomics, Laboratory of Pharmaceutical Biotechnology, Faculty of Pharmaceutical Sciences, Ghent University, Belgium. (1)
Vanderbilt UniversityAssistant Professor of Pharmacology Assistant Professor of Pharmacology, Molecular Physiology and Biophysics Vanderbilt Brain Institute Vanderbilt Center for Addiction Research Vanderbilt Institute for Infection, Immunology and Inflammation (1)
Department of Neurology,Neurosciences Centre,All India Institute of Medical Sciences,Ansari Nagar, New Delhi-110029, India (1)
Department of Biochemistry Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA (1)
Universidad Simón Bolívar, Facultad de Ciencias Básicas y Biomédicas, Centro de Investigaciones en Ciencias de la Vida, Barranquilla, Colombia (1)
Department of Ecology and Genetics, Uppsala University (1)

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Sex-dependent metabolic remodeling of kidneys revealed by arteriovenous metabolomics

Sex is a fundamental biological variable important in biomedical research, drug development, clinical trials, and prevention approaches. Among many organs, kidneys are known to exhibit remarkable structural, histological, and pathological differences between sexes. However, whether and how kidney...

2026-03-04 | MTBLS13977 | MetaboLights

Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress

Depression and anxiety disorders are more prevalent in females, but the majority of research in animal models, the first step in finding new treatments, has focused predominantly on males. Here we report that exposure to subchronic variable stress (SCVS) induces depression-associated behaviors in fe...

ORGANISM(S): Mus musculus

2016-08-04 | E-GEOD-85136 | biostudies-arrayexpress

Modulation of Recovery from Neonatal Hyperoxic Lung Injury by Sex as a Biological Variable

PRJNA997284 | ENA

Role of sex as a biological variable in neonatal alveolar macrophages

PRJNA1111874 | ENA

Endothelial to Mesenchymal Transition in Neonatal Hyperoxic Lung Injury: Role of sex as a biological variable

PRJNA962106 | ENA

Complete dosage compensation and sex-biased gene expression in Manduca sexta

Using 4 replicate males and 4 replicate females this experiment examined dosage compensation and sex-biased gene expression. Briefly we performed a de novo assembly of the Manduca sexta transcriptome using all sequenced libraries, quantified genes expression, identified the physical locations of gen...

ORGANISM(S): Manduca sexta

2014-03-18 | E-MTAB-2066 | biostudies-arrayexpress

Consideration of sex as a biological variable in diabetes research across twenty years.

Not available

S-EPMC10895746 | biostudies-literature

Modulation of Recovery from Neonatal Hyperoxic Lung Injury by Sex as a Biological Variable

Recovery from lung injury during the neonatal period requires the orchestration of many biological pathways. Modulation of biological pathways can drive the developing lung towards proper repair or persistent maldevelopment after injury that can lead to a disease phenotype. Sex as a biological varia...

ORGANISM(S): Mus musculus

2023-11-15 | GSE237944 | GEO

Acute brain injury and nanomedicine: sex as a biological variable.

Not available

S-EPMC11500709 | biostudies-literature

Considering sex as a biological variable in preclinical research.

Not available

S-EPMC6191005 | biostudies-literature

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698 Results

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Organisms

Repository

Tissue

Disease

Technology Type

Instrument Platform

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CHEBI ID

Metabolite Name

First Public Date

Study type

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