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TranscriptomicsGene expression study identifies important protective pathways utilized by appendicitis and appendectomy for ameliorating colitis
BACKGROUND: Appendicitis followed by appendectomy (AA) at a young age protects against later inflammatory bowel disease (IBD). Using a novel murine appendicitis model we earlier demonstrated that AA proffered significant protection against subsequent experimental colitis. AIM: To delineate genes and...
ORGANISM(S): Mus musculus 
2010-09-01 | E-GEOD-23914 | biostudies-arrayexpress
UnknownRecording brain responses to TMS of primary motor cortex by EEG - utility of an optimized sham procedure.
Not available
S-EPMC8752966 | biostudies-literature
TranscriptomicsTranscription profiling of ischemia-reperfused Rattus norvegicus heart tissue samples
Rats underwent surgery for LAD ligation for 30 min followed by reperfusion. Heart ventricles were collected 2d or 7d after reperfusion. Experiment Overall Design: rats were divided in following groups that underwent LAD occlusion or not (SHAM): Experiment Overall Design: 1. 7d-IR (n=3) Experiment O...
ORGANISM(S): Rattus norvegicus 
2007-11-06 | E-GEOD-4105 | biostudies-arrayexpress
TranscriptomicsLeft ventricular myocardial transcriptomic profiling for target discovery in a rat model of pressure overload-induced heart failure
Left ventricular myocardial transcriptomic profiling was performed in rats subjected to transverse aortic constriction (TAC)-induced heart failure and sham-operated controls to investigate gene expression changes associated with pressure overload-induced cardiac remodeling. The dataset was used in s...
ORGANISM(S): Rattus norvegicus 
2026-06-11 | E-MTAB-17114 | biostudies-arrayexpress
TranscriptomicsThrombopoietin (TPO) protects against heart damage induced infarction in rat model
In order to examine the mechanism of TPO on cardiac protection against myocardial infarction damage (MI), we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to delineate the TPO cardioprotective mechanism against infarction. MI ...
ORGANISM(S): Rattus norvegicus 
2012-12-01 | E-GEOD-22489 | biostudies-arrayexpress
UnknownEffects of exogenous recombinant APC in mouse models of ischemia reperfusion injury and of atherosclerosis.
Not available
S-EPMC4102480 | biostudies-literature
UnknownPrenatal maternal immune activation causes epigenetic differences in adolescent mouse brain.
Not available
S-EPMC4203009 | biostudies-literature
TranscriptomicsIs Increased Sinusoidal Flow in the Liver Remnant the primary Stimulus to Regeneration after partial Hepatectomy
The impact of portal arterialization on the liver parenchyma was studied in a series of six pigs with aortoportal shunting of liver segments II, III and IV (and 6 sham animals). Gene expression in the arterialized segments was compared to expression in sham animals. Primary endpoints were gene expre...
ORGANISM(S): Sus scrofa 
2010-05-07 | E-GEOD-13683 | biostudies-arrayexpress
UnknownA soluble and highly fermentable dietary fiber with carbohydrases improved gut barrier integrity markers and growth performance in F18 ETEC challenged pigs1.
Not available
S-EPMC6488326 | biostudies-literature
MetabolomicsIntegrated Proteomics and Metabolomics Analyses Revealed Potential Phospholipid-Related Biomarkers in Rabbit Atherosclerotic Plaques

BACKGROUND AND AIMS: Atherosclerosis, characterized by dysfunction of lipid metabolism and chronic inflammation, is considered as a metabolic disorder as well as a major contributor to cardiovascular diseases. However, metabolic signatures of atherosclerosis have not been well ex...

2024-09-26 | MTBLS9737 | MetaboLights
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