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ProteomicsASO treated adult Shank2 KO mice phosphoproteome
Decreased NMDA receptor function is a central mechanism implicated in various brain disorders, and extensive efforts to modulate NMDAR activity have been devoted in various therapeutic settings. We have previously established Slc6a20a as a novel glycine transporter, and using an antisense oligonucle...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-24 | PXD061254 | Pride
Slc6a20a Aso Shank2 ko 
ProteomicsASO-treated Shank2 KO mice total proteomic data
Decreased NMDA receptor function is a central mechanism implicated in various brain disorders, and extensive efforts to modulate NMDAR activity have been devoted in various therapeutic settings. We have previously established Slc6a20a as a novel glycine transporter, and using an antisense oligonucle...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-24 | PXD061252 | Pride
Slc6a20a Shank2 Aso 
ProteomicsASO-treated Shank3 KO mice phosphoproteome
Decreased NMDA receptor function is a central mechanism implicated in various brain disorders, and extensive efforts to modulate NMDAR activity have been devoted in various therapeutic settings. We have previously established Slc6a20a as a novel glycine transporter, and using an antisense oligonucle...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-24 | PXD061261 | Pride
Slc6a20a Aso Shank3 ko 
TranscriptomicsTranscriptome analysis of Shank2 mutant mice
Autism spectrum disorders (ASDs) are a group of developmental disorders that cause variable and heterogeneous phenotypes across three behavioral domains such as atypical social behavior, disrupted communications, and highly restricted and repetitive behaviors. In addition to these core symptoms, oth...
ORGANISM(S): Mus musculus 
2017-01-24 | GSE79824 | GEO
UnknownIdentification of a novel Shank2 transcriptional variant in Shank2 knockout mouse model of autism spectrum disorder.
Not available
S-EPMC7132969 | biostudies-literature
UnknownDifferentially altered social dominance- and cooperative-like behaviors in Shank2- and Shank3-mutant mice.
Not available
S-EPMC7602353 | biostudies-literature
UnknownDistinct Phenotypes of Shank2 Mouse Models Reflect Neuropsychiatric Spectrum Disorders of Human Patients With SHANK2 Variants.
Not available
S-EPMC6060255 | biostudies-literature
UnknownEarly Chronic Memantine Treatment-Induced Transcriptomic Changes in Wild-Type and Shank2-Mutant Mice.
Not available
S-EPMC8477010 | biostudies-literature
ProteomicsASO-treated Shank3 HT mice proteome
Decreased NMDA receptor function is a central mechanism implicated in various brain disorders, and extensive efforts to modulate NMDAR activity have been devoted in various therapeutic settings. We have previously established Slc6a20a as a novel glycine transporter, and using an antisense oligonucle...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-24 | PXD061255 | Pride
Shank3 ht Slc6a20a Aso 
GenomicsMus musculus
Transcriptome analysis of Shank2 mutant mice
PRJNA317068 | ENA
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