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TranscriptomicsChronic Pentylenetetrazol treatment induced successive gene expression changes in Drosophila head
Pentylenetetrazol (PTZ)-induced kindling in rodents is an established model of epileptogenesis. The molecular basis of the associated long-term plasticity is however not clear. Further, rodent models of kindling plasticity are not amenable to large-scale screening of compounds for identifying antiep...
ORGANISM(S): Drosophila melanogaster 
2007-10-01 | E-GEOD-7120 | biostudies-arrayexpress
TranscriptomicsControl cDNA microarray profiles of Drosophila head
In the process of developing a biological systems model of kindling-like plasticity in the fruit fly, we performed a control gene expression profiling analysis in which RNA isolated from different pools of heads of wild-type flies grown on normal food (NF) were compared between themselves using cDNA...
ORGANISM(S): Drosophila melanogaster 
2007-10-01 | E-GEOD-7037 | biostudies-arrayexpress
TranscriptomicsA regulatory hierarchy controls the dynamic transcriptional response to extreme oxidative stress in archaea.
Previous work identified the winged helix-turn-helix DNA binding transcription factor (TF) RosR (encoded by VNG0258H gene), which dynamically regulates expression of more than 300 genes in response to oxidative stress in Halobacterium salinarum (Sharma 2012). RosR is required for survival of oxidant...
ORGANISM(S): Halobacterium sp. NRC-1 
2015-02-18 | E-GEOD-58696 | biostudies-arrayexpress
TranscriptomicsA systematic search for transgenerational effect of drug exposure to adult males using a novel Drosophila model
Drosophila melanogaster adult flies fed on food containing 16 mg/ml of pentylenetetrazole (PTZ) in the food show a hyperkinetic behavior within 24 hours. Half of that concentration, i.e., 8 mg/ml, of PTZ, if fed for seven days, though doesn’t cause seizure-like behavior, results in a decreased climb...
ORGANISM(S): Drosophila melanogaster 
2009-03-25 | E-GEOD-15136 | biostudies-arrayexpress
UnknownSilencing Myeloid Netrin-1 Induces Inflammation Resolution and Plaque Regression.
Not available
S-EPMC8529357 | biostudies-literature
UnknownShort versus standard peroral endoscopic myotomy for esophageal achalasia: a systematic review and meta-analysis.
Not available
S-EPMC8375650 | biostudies-literature
UnknownAttraction of Sweet Potato Whitefly, <i>Bemisia tabaci</i> (Hemiptera: Aleyrodidae), and Two Generalist Predators to Green Leaf Volatile Compounds.
Not available
S-EPMC11508912 | biostudies-literature
TranscriptomicsGene expression changes in Drosophila head secondary to sodium valproate treatment during Pentylenetetrazole withdrawal.
Drosophila melanogaster adult flies fed on normal food (NF) containing 16 mg/ml of pentylenetetrazole (PTZ) in the food show a hyperkinetic behavior within 24 hours. Half of that concentration, i.e., 8 mg/ml, of the PTZ, if fed for seven days, though doesn’t cause seizure-like behavior, results in a...
ORGANISM(S): Drosophila melanogaster 
2008-05-03 | E-GEOD-10986 | biostudies-arrayexpress
TranscriptomicsGene expression changes in Drosophila head secondary to levetiracetam treatment during Pentylenetetrazole withdrawal.
Drosophila melanogaster adult flies fed on normal food (NF) containing 16 mg/ml of pentylenetetrazole (PTZ) in the food show a hyperkinetic behavior within 24 hours. Half of that concentration, i.e., 8 mg/ml, of the PTZ, if fed for seven days, though doesn’t cause seizure-like behavior, results in a...
ORGANISM(S): Drosophila melanogaster 
2008-05-03 | E-GEOD-10988 | biostudies-arrayexpress
TranscriptomicsGene expression changes in Drosophila head secondary to gabapentin treatment during Pentylenetetrazole withdrawal.
Drosophila melanogaster adult flies fed on normal food (NF) containing 16 mg/ml of pentylenetetrazole (PTZ) in the food show a hyperkinetic behavior within 24 hours. Half of that concentration, i.e., 8 mg/ml, of the PTZ, if fed for seven days, though doesn’t cause seizure-like behavior, results in a...
ORGANISM(S): Drosophila melanogaster 
2008-05-03 | E-GEOD-10985 | biostudies-arrayexpress
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