Sort   by:  
 Page size 
TranscriptomicsComparative transcriptome analysis of Saccharomyces cerevisiae wild type and M-NM-^Tasc1 strain
Asc1p and its essential orthologues in higher eukaryotes, as e.g. RACK1 in mammals, are involved in several distinct cellular signaling processes, but the implications of a total deletion have never been assessed in a comprehensive genome-wide manner. This study reveals the major cellular processes ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-11-30 | E-GEOD-34286 | biostudies-arrayexpress
TranscriptomicsGenome wide analysis of Histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene
Epigenetic deregulation plays a critical role in the pathogenesis of Acute Myeloid Leukemia. But changes in histone modification patterns at the epigenome level still remain largely unknown. Here, we analyzed alterations of histone H3 acetylation patterns in a large number of patients with AML compa...
ORGANISM(S): Homo sapiens 
2011-12-16 | E-GEOD-27863 | biostudies-arrayexpress
TranscriptomicsDevelopmentally regulated lncRNAs expression in male germline
To decipher the roles of non-coding RNAs during male germline development, we use the lncRNAs microarray to profile the genome-wide lncRNAs expression pattern in the male germline Testes samples from 6 time points were collected for lncRNAs and mRNAs microarray profiling
ORGANISM(S): Mus musculus 
2013-06-30 | E-GEOD-46896 | biostudies-arrayexpress
TranscriptomicsEnhanced CLIP uncovers IMP protein-RNA targets in human pluripotent stem cells important for cell adhesion and survival [eCLIP-Seq]
Human pluripotent stem cells (hPSCs) require precise control of post-transcriptional RNA networks to maintain proliferation and survival. Using a recently developed enhanced UV crosslinking and immunoprecipitation (eCLIP) approach, we identify RNA targets of the IMP/IGF2BP family of RNA-binding prot...
ORGANISM(S): Homo sapiens 
2016-04-07 | E-GEOD-78507 | biostudies-arrayexpress
TranscriptomicsGastric cancers of Western European and African patients
Gastric cancer is the second most common cause of cancer death worldwide, but incidence and mortality rates show large variations across different countries. Variation in risk factors between different populations, including environmental and host factors influencing gastric cancer risk, have been r...
ORGANISM(S): Homo sapiens 
2011-06-27 | E-GEOD-22789 | biostudies-arrayexpress
TranscriptomicsLosses of chromosome 5q and 14q mark a subset of gastric cancers with good clinical outcome
Purpose: To improve clinical outcome of gastric cancer patients, most emphasis is on improving therapeutic regimens, including more extensive surgery as well as (neo)adjuvant chemotherapy. The present study set out to identify, based on DNA copy number profiling, subgroups of patients with different...
ORGANISM(S): Homo sapiens 
2012-05-09 | E-GEOD-26389 | biostudies-arrayexpress
TranscriptomicsControl shRNA- vs. obscurin shRNA-expressing MCF10A cells
Obscurins (~70-870kDa), encoded by the single OBSCN gene, are cytoskeletal proteins originally identified in striated muscles with structural and regulatory roles. Recently, analysis of 13,023 genes in breast and colorectal cancers identified OBSCN as one of the most frequently mutated genes, impli...
ORGANISM(S): Homo sapiens 
2012-02-02 | E-GEOD-35494 | biostudies-arrayexpress
TranscriptomicsExpression analysis of Clostridium acetobutylicum ATCC 824 grown on different carbohydrates
Investigation of whole genome gene expression levels in Clostridium acetobutylicum strain 824 grown individually on starch, galactose, lactose, mannose, fructose, glucose, arabinose, xylose, cellobiose, maltose, sucrose A 33 array study using total RNA recovered from three separate wild-type cultur...
ORGANISM(S): Clostridium acetobutylicum ATCC 824 
2010-05-15 | E-GEOD-18471 | biostudies-arrayexpress
TranscriptomicsSex differences in the translatome of Drosophila fruitless-expressing neurons that underlie reproductive behaviors
Adult reproductive behaviors in Drosophila melanogaster males and females are vastly different. Yet, neurons that express sex-specifically spliced fruitless transcripts (fru P1) underlie these behaviors in both sexes. How the same set of neurons can drive such different behaviors is an important an...
ORGANISM(S): Drosophila melanogaster 
2015-09-01 | E-GEOD-67743 | biostudies-arrayexpress
TranscriptomicsDifferentiated mouse podocytes (SVI)
Transcriptomes of differentiated cells of the conditionally immortalized mouse podocyte cell line SVI (Schiwek et al., Kidney Int. 66: 91-101, 2004) were determined as described in Kabgani et al. (PLoS One 7:e34907, 2012). The transcriptomes of the podocyte cell line were mapped on a protein-protein...
ORGANISM(S): Mus musculus 
2012-10-16 | E-GEOD-41523 | biostudies-arrayexpress
Sort   by:  
 Page size