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Quantitative phosphoproteomic analysis of overexpressing PPP1R12B and control Huh7 cells samples using 4D-SmartDIA.
ORGANISM(S): Homo Sapiens 
2025-06-10 | PXD064803 |
The mass spectrometry analysis was performed by Micrometer Biotech Company. Endogenous human GLI1 from Daoy cells was enriched by co-immunoprecipitation with anti-Gli1 and purified by SDS-PAGE. The gel was then stained with Coomassie brilliant blue, and the corresponding visualized bands were excise...
ORGANISM(S): Homo Sapiens 
2023-10-25 | PXD046374 |
Mutations or aberrant upregulation of the histone methyltransferase EZH2 occur frequently in human cancers yet EZH2-targeted therapies have only shown very limited clinical benefits in hematological malignancies. We report here that upon EZH2 inhibition, MLL1 interacts with p300/CBP complex that dir...
ORGANISM(S): Homo Sapiens 
2018-09-10 | PXD010842 |
An unbiased quantitative phosphoproteomics analysis in 16HBE cells treated with or without IL-13 and 2-D08.
ORGANISM(S): Homo Sapiens 
2023-06-08 | PXD042842 |
This model looks at the development of colitis-associated colon cancer in order investigate the mechanism behind inflammation-associated tumorigenesis. Dynamic simulations reveal that P53, MDM2, and AKT may constitute a core network responsible for the malignant transformation of colon epithelial ce...
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