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ProteomicsProteomic and Phosphoproteomic Sequencing of NRK-49F Cells after TGF-β1 Stimulation: Impact of USP7 Knockout
Dysregulation of the expression of ubiquitin - specific protease 7 (USP7) has been associated with tumor progression. However, the biological functions and clinical significance of USP7 in renal fibrosis remain insufficiently explored. In this study, proteomic and phosphoproteomic sequencing were pe...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-09-07 | PXD059829 | Pride
Nrk-49f usp7 
TranscriptomicsTranscription profiling of mouse presenilin conditional double knockout cerebral cortex at 6 months old
Gene expression profile of presenilin conditional double knockout cerebral cortex, comparing to control. Age of mice: 6 months
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-1375 | biostudies-arrayexpress
ProteomicsMulti-Omics Analysis Reveals RNA Polymerase II Degradation as a Novel Mechanism of PF-3758309's Anti-Tumor Activity
In this study, we conducted a comprehensive multi-omics analysis, including proteomics, transcriptomics, and ubiquitinomics, to investigate the mechanism of PF-3758309 in HCT116 cells. Our results revealed that PF-3758309 promotes the degradation of RNA polymerase II subunit proteins (POLR2A/B/E) vi...
ORGANISM(S): Homo Sapiens 
2025-06-05 | PXD064705 |
ProteomicsIdentification of candidate microRNA biomarkers of endometriosis in different bodily fluids
Endometriosis is a common gynecological condition that affects approximately 10% of women of reproductive age and up to half of those experiencing infertility. However, there is a lack of reliable noninvasive diagnostic tools for diagnosing endometriosis. This study aims to identify novel biomarkers...
ORGANISM(S): Homo Sapiens 
2025-11-17 | PXD070868 |
UnknownPrevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study.
Not available
S-EPMC7880913 | biostudies-literature
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