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ProteomicsSIRT3 interactions and mitochondrial proteome during HCMV infection
SIRT3 has been shown to inhibit HCMV infection, but the mechanism under the antiviral effect is not clear. To identify the mediator of SIRT3 antiviral function, we aim to identify and quantify SIRT3 interactions during HCMV infection. A set of large-scale IPs were performed to determine the specific...
ORGANISM(S): Homo sapiens (Human) 
2021-04-01 | PXD018995 | Pride
Hcmv Mitochondrial proteome Ip-ms Sirt3 
ProteomicsGenetic mechanisms of cardiac sex diparities
Male and female disease states differ in their prevalence, treatment responses, and survival rates. In cardiac disease, women almost uniformly fare far worse than men1-3. Though sex plays a critical role in cardiac disease, the mechanisms underlying sex differences in cardiac homeostasis and disease...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-11 | PXD020139 | Pride
Mouse heart Sex disparities 
ProteomicsPRM quantification of MCS proteins and viral proteins in HCMV virus microenvironment
The control of host processes which influence cell-cell communication is central to determining the outcome of a virus infection in tissue. Despite this, it remains unclear how cells either in close or distant proximity to an infected cell differentially respond to the primary infection. We establis...
ORGANISM(S): Homo Sapiens Human Betaherpesvirus 5 
PXD038466 | panorama
ProteomicsProteomic of control and FBL knockdown C4-2 cells
We employed a quantitative proteomics approach to compare the protein expression levels between control and FBL knockdown C4-2 cells, revealing expression levels of some proteins which have decreased mRNA half-life.
ORGANISM(S): Homo Sapiens 
2024-03-17 | PXD050701 |
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