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TranscriptomicsDual-transcriptome of Shigella flexneri infecting human HCT116 cells
Analyse the transcriptionnal changes of human colon epithelial cells (HCT116) associated with Shigella flexneri (M90T) infection and correlated with the bacterial transcriptional program.
ORGANISM(S): Homo sapiens 
2024-12-01 | E-MTAB-14119 | biostudies-arrayexpress
TranscriptomicsExpression analysis of Shigella flexneri 2a strain 301
Investigation of whole genome gene expression to identify overlooked sRNAs and sORFs. Background The completion of numerous genome sequences has introduced an era of whole-genome study. However, many real genes, including small RNAs (sRNAs) and small ORFs (sORFs), are missed in genome annotation. In...
ORGANISM(S): Shigella flexneri 2a str. 301 
2011-06-27 | E-GEOD-22800 | biostudies-arrayexpress
ProteomicsQuantitative proteomic analysis of Shigella flexneri and Shigella sonnei Generalized Modules for Membrane Antigens (GMMA) reveals highly pure preparations.
Shigella flexneri 2a and Shigella sonnei were genetically modified to shed large quantities of outer membrane blebs. The blebs, called Generalized Modules for Membrane Antigens (GMMA), were purified and the protein content was estimated using the label-free iBAQ procedure. There were 2308 proteins i...
ORGANISM(S): Shigella flexneri 2a str. 2457T Shigella sonnei 53G 
2016-01-12 | PXD002517 | Pride
Shigella flexneri Label-free quantification Shigella sonnei. lc-ms/ms 
ProteomicsProtein identification of BS3 crosslinked Shigella flexneri type III secretion system needle complex
Protein identification of BS3 crosslinked Shigella flexneri type III secretion system needle complex
ORGANISM(S): Shigella flexneri 5a 
2026-05-05 | PXD038227 | Pride
Shigella flexneri Type iii secretion system needle complex 
TranscriptomicsExpression data from wild type and deltaS4473 Shigella flexneri 2457T
Comparison of wild type S. flexneri 2457T gene expression to deletion mutant of S. flexneri 2457T gene S4473 at three growth phases and intracellularly Broth culture was grown to mid-log in LB, intracellular growth was 3 hours post invasion of HCT-8 cell (colonic epithelial cell line).
ORGANISM(S): Shigella flexneri 2a str. 2457T 
2013-10-18 | E-GEOD-40851 | biostudies-arrayexpress
TranscriptomicsIdentification of IFNg-regulated, IRF1-dependent genes in Shigella flexneri-infected mouse embryonic fibroblasts (MEFs)
This experiment was designed to identify IFNg-regulated, IRF1-dependent genes during infection with the intracellular pathogen Shigella flexneri. WT and Irf1-/- MEFs were stimulated for 18 hours with IFNg or left unstimulated; all of the cells were subsequently infected for 6 hours with S. flexneri...
ORGANISM(S): Mus musculus 
2011-09-01 | E-MTAB-713 | biostudies-arrayexpress
TranscriptomicsRNA polymerase inhibitor
Global transcriptional responses of shigella flexneri to RNA poly merase inhibitor We used two drugs with two concentration. At each concentration, there 3 time points.
ORGANISM(S): Shigella flexneri 
2012-03-21 | E-GEOD-32978 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling of human colon cells infected with the bacterium Shigella flexneri
Overview of microRNA expression changes during Shigella flexneri infection of human colon epithelial cells (HCT116)
ORGANISM(S): Homo sapiens 
2024-12-01 | E-MTAB-14092 | biostudies-arrayexpress
GenomicsShigella flexneri
Shigella flexneri Raw sequence reads
PRJNA527970 | ENA
GenomicsShigella flexneri
Shigella flexneri Raw sequence reads
PRJNA998171 | ENA
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