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ProteomicsArchaea produce peptidoglycan hydrolases that kill bacteria
The social life of archaea is poorly understood. In particular, even though competition and conflict are common themes in microbial communities, there is scant evidence documenting antagonistic interactions between archaea and their abundant prokaryotic brethren: bacteria. Do archaea specifically ta...
ORGANISM(S): Haloferax volcanii SB1 
2026-02-07 | PXD064732 | Pride
Archaea Peptidoglycan hydrolase 
ProteomicsMiddle-Down Proteomic Analyses with Ion Mobility Separations of Endogenous Isomeric Proteoforms
We integrated FAIMS into the WCX-HILIC ETD MS/MS system to improve identification of histonetail proteforms
ORGANISM(S): Mus musculus (Mouse) 
2020-04-02 | PXD016918 | Pride
Faims Histones Etd Middle down 
ProteomicsPRMT5 methylome profiling uncovers a direct link to splicing regulation in human acute myeloid leukemia
Protein arginine methyltransferase 5 (PRMT5) belongs to the class II arginine methyltransferases and catalyzes monomethylation and symmetrical dimethylation of arginines on proteins. It has recently emerged as a promising cancer drug target, and two PRMT5 inhibitors are currently in clinical trials ...
ORGANISM(S): Homo sapiens (Human) 
2019-11-08 | PXD013611 | Pride
Prmt5 Tmt Arginine methylation Ptm Human 
ProteomicsComplex-dependent histone acetyltransferase activity of KAT8 determines its role in transcriptional regulation and cellular homeostasis [histone dataset]
Histone acetylation is associated with open chromatin and transcriptionally active genes. Specifically, acetylation of lysine 16 on histone H4 (H4K16ac) has been shown to prevent the assembly of nucleosomal arrays in vitro. This modification is catalyzed by the MYST-family histone acetyltransferase ...
ORGANISM(S): Homo sapiens (Human) 
2021-06-29 | PXD021943 | Pride
Nsl Msl Histone Kat8 
ProteomicsComplex-dependent histone acetyltransferase activity of KAT8 determines its role in transcriptional regulation and cellular homeostasis [TMT11plex whole proteome analysis]
Histone acetylation is associated with open chromatin and transcriptionally active genes. Specifically, acetylation of lysine 16 on histone H4 (H4K16ac) has been shown to prevent the assembly of nucleosomal arrays in vitro. This modification is catalyzed by the MYST-family histone acetyltransferase ...
ORGANISM(S): Homo sapiens (Human) 
2021-06-29 | PXD023865 | Pride
Nsl Msl Histone Kat8 
ProteomicsComplex-dependent histone acetyltransferase activity of KAT8 determines its role in transcriptional regulation and cellular homeostasis [AP-MS]
Histone acetylation is associated with open chromatin and transcriptionally active genes. Specifically, acetylation of lysine 16 on histone H4 (H4K16ac) has been shown to prevent the assembly of nucleosomal arrays in vitro. This modification is catalyzed by the MYST-family histone acetyltransferase ...
ORGANISM(S): Homo sapiens (Human) 
2021-06-29 | PXD022267 | Pride
Nsl Msl Histone Kat8 
ProteomicsStreptomyces coelicolor quantitative proteome and phosphoproteome analyses reveal proteins and phosphoproteins modulating differentiation and secondary metabolism
Investigation of proteome and phosphoproteome changes during Streptomyces coelictor life cycle using TMT tagging and calcium precipitation - titanium dioxide enrichment
ORGANISM(S): Streptomyces coelicolor 
2018-05-25 | PXD005558 | Pride
Streptomyces coelicolor Phosphoproteomics Tio2 
ProteomicsScoelicolor A3(2) - Whole organism, SC (Rioserasetal,molcellproteomics2018)
abundance based on Spectral counting, Interaction consistency score: 11.4, Coverage: 45
ORGANISM(S): 100226 
2018-00-00 | 3401610947 | PAXDB
ProteomicsScoelicolor A3(2) - Whole organism, normlized TMT (Rioserasetal,molcellproteomics2018)
abundance based on normlized TMT, Interaction consistency score: 8.2, Coverage: 45
ORGANISM(S): 100226 
2018-00-00 | 3141927513 | PAXDB
ProteomicsScoelicolor A3(2) - Whole organism, SC (Rioserasetal,molcellproteomics2018)
abundance based on Spectral counting, Interaction consistency score: 7.0, Coverage: 45
ORGANISM(S): 100226 
2018-00-00 | 3389253060 | PAXDB
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