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TranscriptomicsExpression analysis of Streptomyces avermitilis NRRL8165 delta-aveI mutant
Investigation of whole genome gene expression level changes in Streptomyces avermitilis delta-aveI mutant, compared to the wild-type strain. The mutants analyzed in this study are further described in Chen L, Lu Y., Chen J, Zhang W, Shu D, Qin Z, Yang S, Jiang W. (2008) Characterization of a negativ...
ORGANISM(S): Streptomyces avermitilis 
2010-05-16 | E-GEOD-16892 | biostudies-arrayexpress
UnknownRegulator of G Protein Signaling 6 Facilities Cardiac Hypertrophy by Activating Apoptosis Signal-Regulating Kinase 1-P38/c-JUN N-Terminal Kinase 1/2 Signaling.
Not available
S-EPMC6404897 | biostudies-literature
MetabolomicsOrganic Acids Modulate Systemic Metabolic Perturbation Caused by Salmonella Pullorum Challenge in Early-Stage Broilers
The objectives of this study were to determine the protective effects of organic acids (OA) in broilers exposed to Salmonella Pullorum challenge at early stage and to explore the potential benefits of OA by metabolomics analysis. The treatment groups included non-challenged, S. Pullorum-challenged, ...
2021-05-17 | MTBLS1274 | MetaboLights
MetabolomicsUntargeted LC-MS metabolomics for the analysis of micro-scaled extracellular metabolites from hepatocytes
Metabolome analysis in micro physiological models is a challenge due to the low volume of cell culture medium (CCM). Here, we report a LC-MS-based untargeted metabolomics protocol for the detection of hepatocyte extracellular metabolites from micro-scale samples of CCM. Using a single LC-MS method w...
2021-01-04 | MTBLS1794 | MetaboLights
ProteomicsPhosphoproteomic analysis of methanoarchaeon Methanohalophilus portucalensis FDF1T reveals diverse functions in methanogenesis and osmoadaptation
Methane is a well-known factor in green house effect and also could be an alternative energy, which produced via methanogenesis by methanogenic archaea. Methanohalophilus portucalensis FDF1T is a halophilic methylotrophic methanogen and has been used as a model to study osmoadaptation in fluctuated ...
ORGANISM(S): Methanohalophilus 
2016-07-05 | PXD002024 | Pride
Methanohalophilus portucalensis Methanogenesis Phosphorylation modificatioin 
UnknownAdipocyte Fatty Acid Binding Protein Promotes the Onset and Progression of Liver Fibrosis via Mediating the Crosstalk between Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells.
Not available
S-EPMC8188197 | biostudies-literature
UnknownThe mechanism of Shancigu and its monomer in the development of colorectal cancer based on network pharmacology.
Not available
S-EPMC12222874 | biostudies-literature
MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Human UPLC-MS/MS assays)

Progressive decline in lung function is a hallmark of chronic obstructive pulmonary disease (COPD). Although airway dysbiosis occurs in COPD, whether it contributes to disease progression remains unknown. Here, through a longitudinal analysis on 181 COPD individuals from two large cohorts involvi...

2023-06-12 | MTBLS5423 | MetaboLights
UnknownNetwork pharmacology, molecular docking and experimental verification help unravel chelerythrine's potential mechanism in the treatment of gastric cancer.
Not available
S-EPMC10336441 | biostudies-literature
UnknownmiR-122 Exerts Inhibitory Effects on Osteoblast Proliferation/Differentiation in Osteoporosis by Activating the PCP4-Mediated JNK Pathway.
Not available
S-EPMC7082497 | biostudies-literature
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