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GenomicsTranscriptomic profile of Sialyl-Lewis X (CD15s)+ basophils and Sialyl Lewis X- basophils
Transcriptomic profile of Sialyl-Lewis X (CD15s)+ basophils and Sialyl Lewis X- basophils
PRJNA504452 | ENA
ProteomicsIdentification of sialyl Lewisa/x-modified surface proteins in Multiple Myeloma cells by LC-MS
The project aims at identifying surface proteins that are modified by the tetrasaccharide sialyl Lewisa/x and therefore serve as selectin ligands in Multiple Myeloma. To that end, we have performed an immunoprecipitation using the Heca452 antibody (which recognizes sialyl Lewisa/x-related structures...
ORGANISM(S): Homo sapiens (Human) 
2024-01-23 | PXD046178 | Pride
Mulriple myeloma Sialyl lewis a/x Selectin ligands 
TranscriptomicsTranscriptomic profile of Sialyl-Lewis X (CD15s)+ basophils and Sialyl Lewis X- basophils
Sialyl Lewis X (sLexX or CD15s) is a tetra-saccharide N-acetylneuraminic acid, galactose, fucose and N-acetylglucosamine (NeuAcα2,3Galβ1,4(Fucα1,3)-GlcNAc). CD15s is present on various leukocytes usually as O-linked glycans bound to surface molecules such as PSGL-1, CD43 and CD44. On leukocytes, CD1...
ORGANISM(S): Homo sapiens 
2021-06-15 | GSE122281 | GEO
UnknownDiscovery of sialyl Lewis A and Lewis X modified protein cancer biomarkers using high density antibody arrays.
Not available
S-EPMC3946870 | biostudies-literature
UnknownExpression of the Carbohydrate Lewis Antigen, Sialyl Lewis A, Sialyl Lewis X, Lewis X, and Lewis Y in the Placental Villi of Patients With Unexplained Miscarriages.
Not available
S-EPMC8202085 | biostudies-literature
UnknownChemoenzymatic synthesis of functional sialyl Lewis(x) mimetics with a heteroaromatic core.
Not available
S-EPMC4498494 | biostudies-literature
TranscriptomicsTo determine the changes in the expression of human colon cancer cells (HCT-15) untreated and treated with 5-aza-2''-deoxycytidine
Human colon cancer cells (HCT-15) treated with 5-aza-2'-deoxycytidine greatly enhanced sialyl Lewis X epitope, which correlated with increased binding of these cells to immobilized E-selectin in a parallel plate dynamic flow binding assay. Human colon cancer cells (HCT-15) treated with 5-aza-2'-deox...
ORGANISM(S): Homo sapiens 
2011-09-05 | E-GEOD-31933 | biostudies-arrayexpress
UnknownGlycan motif profiling reveals plasma sialyl-lewis x elevations in pancreatic cancers that are negative for sialyl-lewis A.
Not available
S-EPMC4424402 | biostudies-literature
UnknownSystematic Chemoenzymatic Synthesis of O-Sulfated Sialyl Lewis x Antigens.
Not available
S-EPMC5269574 | biostudies-literature
ProteomicsO-linked glicoproteomics of gastric cancer cell lines OCUM-1, N87 and KATO-III
Gastric cancer (GC) is the third leading cause of cancer-related death worldwide, continuously requiring innovative target therapies. The sialyl-lewis A (SLeA) antigen offers tremendous potential for precise cancer targeting. This glycan is rarely expressed by healthy tissues and blood cells but is ...
ORGANISM(S): Homo sapiens (Human) 
2020-05-11 | PXD016968 | Pride
Human Glycoproteomics Sialyl-lewis a Gastric cancer Cell lines Lc-ms/ms 
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