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TranscriptomicsExpanding epigenomics to archived FFPE tissues: An evaluation of DNA repair methodologies
A study to evaluate techniques for repairing DNA from formalin-fixed paraffin-embedded (FFPE) tissue samples by direct comparison of FFPE DNA repair methods prior to analysis on genome-wide methylation array to matched fresh frozen (FF) tissues. Formalin-fixed paraffin-embedded tissue from three col...
ORGANISM(S): Homo sapiens 
2014-12-17 | E-GEOD-59038 | biostudies-arrayexpress
TranscriptomicsApplied Biosystems Human TaqMan Low Density Array (TLDA) in plasma samples from HCC cases and controls
MicroRNAs (miRNAs) are abundant in the circulation and play a central role in diverse biological processes; they may be useful for early diagnosis of hepatocellular carcinoma (HCC). We conducted a two-phase, case-control study (20 pairs for the discovery set and 49 pairs for the validation set) to t...
ORGANISM(S): Homo sapiens 
2013-08-21 | E-GEOD-50013 | biostudies-arrayexpress
TranscriptomicsApplied Biosystems Human TaqMan Low Density Array (TLDA) in HCC tumor and adjacent non-tumor tissues
MicroRNAs (miRNAs) are aberrant expressed in hepatocellular carcinoma (HCC) tissue and play a central role in diverse biological processes. We conducted a genome-wide miRNAs screening in 10 pairs of HCC tumor and adjacent non-tumor tissues to test the hypothesis that dysregulation of miRNAs in HCC t...
ORGANISM(S): Homo sapiens 
2014-02-08 | E-GEOD-54751 | biostudies-arrayexpress
MetabolomicsCoupled Mass-Spectrometry-Based Lipidomics Machine Learning Approach for Early Detection of Clear Cell Renal Cell Carcinoma

A discovery-based lipid profiling study of serum samples from a cohort that included patients with clear cell Renal Cell Carcinoma (ccRCC) stage I, II, III, and IV (n=112) and controls (n=52) was performed using ultraperformance liquid chromatography coupled to quadrupole-time-of-flight mass spec...

2020-11-20 | MTBLS1839 | MetaboLights
TranscriptomicsTranscription profiling of peripheral blood leukocyte subsets in autoimmune/autoinflammatory disease patients and healthy controls
Gene expression microarray profiling was performed on peripheral blood leukocyte subsets (CD4+ T cells, CD14+ monocytes, and CD16+ neutrophils) from healthy controls and patients with flaring autoimmune disease.
ORGANISM(S): Homo sapiens 
2014-08-31 | E-MTAB-2452 | biostudies-arrayexpress
UnknownImpaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome.
Not available
S-EPMC1986664 | biostudies-literature
UnknownCold-inducible RNA-binding protein is associated with subtype-specific breast cancer patient outcomes.
Not available
S-EPMC12363121 | biostudies-literature
UnknownFas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction.
Not available
S-EPMC5196435 | biostudies-literature
UnknownEfficacy and safety of remibrutinib, a selective potent oral BTK inhibitor, in Sjogren's syndrome: results from a randomised, double-blind, placebo-controlled phase 2 trial.
Not available
S-EPMC10894844 | biostudies-literature
UnknownSpontaneous Secretion of the Citrullination Enzyme PAD2 and Cell Surface Exposure of PAD4 by Neutrophils.
Not available
S-EPMC5622307 | biostudies-literature
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