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Chronic stress response activation impairs cell survival and causes devastating degenerative di-seases. To counteract this, cells deploy dedicated silencing factors, such as the E3 ligase SIFI that terminates the mitochondrial stress response. How a single enzyme can sense stress across cellular sca...
ORGANISM(S): Homo sapiens (Human) 
2025-04-16 | PXD055759 | Pride
Stress response pathways detect and alleviate many adverse conditions to safeguard cell and tissue homeostasis, yet their prolonged activation induces apoptosis and disrupts organismal health. How stress responses are turned off at the right time and place remains poorly understood. Here, we report ...
ORGANISM(S): Homo sapiens 
2023-11-22 | GSE232191 | GEO
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