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MetabolomicsLiquid chromatography coupled to high-resolution mass spectrometry metabolomics: A useful tool for investigating tumor secretome based on a three-dimensional co-culture model

Three-dimensional (3D) cell culture technologies, which more closely mimic the complex microenvironment of tissue, are being increasingly evaluated as a tool for the preclinical screening of clinically promising new molecules, and studying of tissue metabolism. Studies of metabolites released int...

2023-12-12 | MTBLS5375 | MetaboLights
MetabolomicsThe Role of Annexin A1 in Candida albicans and Candida auris infections in murine neutrophils

Annexin A1 (AnxA1) is an anti-inflammatory protein present in different cells in biological systems, especially expressed in macrophages and neutrophils. Since neutrophils play an important role in infections and inflammatory processes and the AnxA1 and its relation in Candida spp. infections is ...

2021-12-03 | MTBLS2288 | MetaboLights
UnknownContribuicoes da vitamina D no tratamento de sintomas depressivos e fatores de risco cardiovascular: protocolo de estudo para um ensaio clinico randomizado, duplo-cego e controlado por placebo.
Not available
S-EPMC6788094 | biostudies-literature
UnknownPyrimido[5,4-d]pyrimidine-Based Compounds as a Novel Class of Antitrypanosomal and Antileishmanial Agents.
Not available
S-EPMC9465711 | biostudies-literature
ProteomicsMass spectrometry based quantitative proteome analyses for the import mutants ppi2 and tic56-1 as well as for spectinomycin treated Arabidopsis thalian plants
We acquired quantitative proteomics data from eight week old ppi2 and tic56-1 mutants as well as from wild type treated with 60 µg/ml spectinomycin and related them to their respective wildtype reference. Protein identification and quantification was performed by data-independent MSE acquisition on ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2016-12-14 | PXD004125 | Pride
Hdmse Tic56-1 Plastid Spectinomycin Plastidic translation Quantitative mass spectrometry Shotgun proteomics Toc-tic-import machinery Hi3 quantification Ppi2 
MetabolomicsUntargeted LC-MS metabolomic studies of Asteraceae species to discover inhibitors of Leishmania major dihydroorotate dehydrogenase

INTRODUCTION: Interesting data about the family Asteraceae as a new source of Leishmania major dihydroorotate dehydrogenase (LmDHODH) inhibitors are presented. This key macromolecular target for parasites causing neglected diseases catalyzes the fourth reaction of the de novo pyr...

2019-10-14 | MTBLS722 | MetaboLights
ProteomicsMetabolomes of Aquimarina (Flavobacteriaceae, Bacteroidetes) Species, Positive Ionization Polarity
Paper title: Insights into the antimicrobial activities and metabolomes of Aquimarina (Flavobacteriaceae, Bacteroidetes) species from the rare marine biosphere Author List: Silva, SG, Paula, P, da Silva, J.P, Mil-Homens, D, Teixeira, MC, Fialho, A, Costa, R, Keller-Costa, T PubMedID: Brief descripti...
ORGANISM(S): Aquimarina (ncbitaxon:290174) 
2022-05-26 | MSV000089550 | MassIVE
MetabolomicsComprehensive lipid analysis of green Arabica coffee beans by LC-HRMS/MS
Lipids play an important role in coffee bean development, coffee brew and in the effects of coffee on human health. They account for around 17% of the dry bean weight and encompass different classes and subclasses, mostly triacylglycerols (TAG) and a minor quantity of phospholipids (PL) and βN-alkan...
2021-11-19 | MTBLS1972 | MetaboLights
UnknownMating system, morphological and genetic evidence endorse clonality as an essential reproductive mode in Daphnopsis filipedunculata (Thymelaeaceae), a dioecious and endemic species from the Amazon.
Not available
S-EPMC11459258 | biostudies-literature
UnknownGenomic Detection of the Emerging, Highly Pathogenic HIV-1 Subtype D in Bahia, Northeast Brazil.
Not available
S-EPMC10458544 | biostudies-literature
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