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ProteomicsE2 Rad6 controls cellular response to oxidative stress
Protein ubiquitination is an essential process that rapidly regulates protein synthesis, function, and fate in dynamic environments. Among its non-proteolytic functions, K63 ubiquitin accumulates in yeast cells exposed to oxidative stress, stalling ribosomes at elongation. K63 ubiquitin conjugates a...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-08-12 | PXD025727 | Pride
Yeast Rad6 Oxidative stress Ubiquitin Translation 
ProteomicsE2 Rad6 controls cellular response to oxidative stress
Protein ubiquitination is an essential process that rapidly regulates protein synthesis, function, and fate in dynamic environments. Among its non-proteolytic functions, K63 ubiquitin accumulates in yeast cells exposed to oxidative stress, stalling ribosomes at elongation. K63 ubiquitin conjugates a...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-08-12 | PXD025726 | Pride
Yeast Rad6 K63 ubiquitin Oxidative stress E1 
ProteomicsK48 ubiquitin selectively targets oxidized proteins in vivo
Ubiquitin is a highly conserved eukaryotic protein responsible for regulating a variety of functions when conjugated to target proteins. Ubiquitin is essential, accumulates during the stress response, and is the canonical signal for protein degradation by the proteasome. Still, the function of ubiqu...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-04-30 | PXD014173 | Pride
K48 ubiquitin Yeast Oxidation Oxidative stress 
ProteomicsLocalized K63 ubiquitin signaling is regulated by VCP/p97 during oxidative stress
Under stress conditions, cells reprogram their molecular machineries to mitigate damage and promote survival. Ubiquitin signaling is globally increased during oxidative stress, controlling protein fate and supporting stress defenses at several subcellular compartments. However, the rules driving sub...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-06-04 | MSV000094932 | MassIVE
ProteomicsSite-specific K63 ubiquitinomics reveals stabilization of ribosomes in response to oxidative stress
Reprograming of protein synthesis is an essential cellular process to tolerate and resist to stressing conditions. A variety of mechanisms are known to regulate translation at initiation but cells can also control proteins synthesis after the initiation checkpoint. We previously showed that K63 ubiq...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-12-06 | PXD004650 | Pride
Ubiquitinomics Yeast Oxidative stress K63 ubiquitin Translation regulation 
ProteomicsK63 polyubiquitination is a new modulator of the oxidative stress response, shotgun data
Ubiquitination is a post-translational modification that signals multiple processes, including protein degradation, trafficking and DNA repair. Polyubiquitin accumulates globally during the oxidative stress response, and this has been mainly attributed to increased ubiquitin conjugation and perturba...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2015-01-26 | PXD000960 | Pride
K63 ubiquitination yeast oxidative stress 
ProteomicsK63 polyubiquitination is a new modulator of the oxidative stress response, SRM data
Ubiquitination is a post-translational modification that signals multiple processes, including protein degradation, trafficking and DNA repair. Polyubiquitin accumulates globally during the oxidative stress response, and this has been mainly attributed to increased ubiquitin conjugation and perturba...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2015-01-26 | PXD000979 | Pride
Q-exactive Yeast Silac Lc-ms/ms 
ProteomicsS.cerevisiae - Whole organism, SC (Silvaetal,natstructmolbiol,2015)
abundance based on Spectral counting, Interaction consistency score: 5.8, Coverage: 10
ORGANISM(S): 4932 
2015-00-00 | 743986671 | PAXDB
UnknownGlobal, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.
Not available
S-EPMC4202387 | biostudies-literature
UnknownRivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial.
Not available
S-EPMC6662613 | biostudies-literature
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