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MetabolomicsInvestigating the Mechanisms of Silver Nanoparticle Toxicity in Daphnia magna: A Multi-Omics Approach
Silver nanoparticles (AgNPs), one of the most common nanomaterials in use today, have been shown to enter the aquatic environment from use of commercially obtained products. Although acute toxicity has been shown in vitro and in vivo, there is still a great deal of uncertainty surrounding the molecu...
2017-05-08 | MTBLS260 | MetaboLights
ProteomicsQuantitative proteomics reveals rapid divergence in the postmating response of female reproductive tracts among sibling species
Fertility depends, in part, on interactions between male and female reproductive proteins inside the female reproductive tract (FRT) that mediate postmating changes in female behavior, morphology, and physiology. Coevolution between interacting proteins within species may drive reproductive incompat...
ORGANISM(S): Drosophila simulans Drosophila mauritiana 
2020-06-25 | PXD017708 | Pride
Drosophila simulans Lc-msms Female reproductive tract Tmt Drosophila mauritiana 
ProteomicsDaphnia pulex_Lysine acetylation
Daphnia (Daphnia pulex) is a small planktonic crustacean and a key constituent of aquatic ecosystems. It is commonly used as a model organism for studying environmental toxic challenges. In the past decade, a Daphnia genomic information and proteomic dataset has been developed. This dataset has expa...
ORGANISM(S): Daphnia pulex (Water flea) 
2016-01-05 | PXD002441 | Pride
D. pulex  lysine acetylation  post-translational modification  proteomics 
UnknownPre-operative urinary cathepsin D is associated with survival in patients with renal cell carcinoma.
Not available
S-EPMC2768081 | biostudies-literature
UnknownRecombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models.
Not available
S-EPMC9196656 | biostudies-literature
MetabolomicsThe metabolic response of marine copepods to environmental warming and ocean acidification in the absence of food
Marine copepods are central to the productivity and biogeochemistry of marine ecosystems. Nevertheless, the direct and indirect effects of climate change on their metabolic functioning remain poorly understood. Here, we use metabolomics, the unbiased study of multiple low molecular weight organic me...
2015-10-13 | MTBLS91 | MetaboLights
ProteomicsIdentification of proximal SUMO-dependent interactors using SUMO-ID
To study the function of SUMOylation and SUMO-SIM interactions for particular substrates poses several challenges. SUMOylation occurs transiently and often in a small percentage of the total copy numbers of a given substrate. Modified proteins can be readily deSUMOylated and SUMO can be recycled and...
ORGANISM(S): Homo sapiens (Human) 
2021-09-21 | PXD021923 | Pride
Human Turbo-id Proximity labeling Sall1 Sumo-id Sumo 
ProteomicsWideband PRM: Highly Accurate and Sensitive Method for High-Throughput Targeted Proteomics
Targeted mass spectrometry (MS) approaches, which are powerful methods for uniquely and confidently quantifying a specific panel of proteins in complex biological samples, play a crucial role in validation and clinical translation of protein biomarkers discovered by global proteomic profiling. Commo...
ORGANISM(S): Homo sapiens (Human) 
2024-08-14 | PXD048271 | Pride
Prm Targeted proteomics Parallel reaction monitoring Absolute quantification 
UnknownReversing chromatin accessibility differences that distinguish homologous mitotic metaphase chromosomes.
Not available
S-EPMC4535684 | biostudies-literature
UnknownNon-targeted GC/MS analysis of exhaled breath samples: Exploring human biomarkers of exogenous exposure and endogenous response from professional firefighting activity.
Not available
S-EPMC8668041 | biostudies-literature
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