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TranscriptomicsSIN3A-regulated LIF-responsive genes in MCF7 cells
Tyrosine phosphorylation is a hallmark for activation of Signal Transducer and Activator of Transcription (STAT) proteins, but their transcriptional activity also depends on other secondary modifications. Type I interferons (IFNs) can activate both the ISGF3 (STAT1:STAT2:IRF9) complex and STAT3, but...
ORGANISM(S): Homo sapiens 
2012-08-01 | E-GEOD-35696 | biostudies-arrayexpress
TranscriptomicsMicroarray gene expression profiling of a fibrosarcoma GPNMB-induced cell line MCA-1-GPNMB at basal condition and in the form of spheroids
The expression of the soluble protein GPNMB (glycoprotein non-metastatic melanoma protein B) induces an aggressive behavior of tumor cells by promoting proliferation and distant spread. The main molecular feature is the over expression of interleukin Il-33. The gene profile of MCA-1-GPNMB and MCA-1-...
ORGANISM(S): Mus musculus 
2020-07-30 | E-MTAB-8082 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNAseq and scTCRseq of human CD8 T cells from blood and skin compartments in Dengue patients
Using a skin-blister induction model established for dengue, we investigated the transcriptional signatures and TCR repertoire of matched CD8 T cells in skin and blood samples
ORGANISM(S): Homo sapiens 
2026-04-14 | E-MTAB-16332 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling in cervical carcinomas, low and high-grade intraepithelial cervical lesions and normal cervical tissues
Background. MicroRNAs (miRNAs) are short (~22 nt) non-coding regulatory RNAs that control gene expression at the translational level. Deregulation of miRNA expression has been discovered in a wide variety of tumours and it is now clear that they contribute to cancer development and progression. This...
ORGANISM(S): Homo sapiens 
2010-08-01 | E-GEOD-19611 | biostudies-arrayexpress
Genomicsena-DATASET-dkfz_b062-23-02-2018-16:41:10:412-192 - samples
This dataset contains ChIP sequencing data from 24 patients. ChIP of 5–10 mg flash-frozen primary ependymoma tumour was performed using 5 mg H3K27ac antibody per ChIP experiment. The enriched DNA has been sequenced on a Illumina HiSeq2000 instrument in paired-end mode. Up to two lanes per sampl...
EGAD00001003979 | EGA
Genomicsena-DATASET-dkfz_b062-16-02-2018-17:18:40:151-347 - samples
This dataset conatains RNA sequencing data from 24 patients. Up to two lanes per tumour sample have been seqeunced on a Illumina HiSeq2000 instrument in paired-end mode resulting in 58 Fastq files.
EGAD00001003966 | EGA
Genomicsena-DATASET-dkfz_b062-31-01-2018-17:04:38:652-360 - samples
This dataset contains whole genome sequencing data from 24 patients. For each patient a tumour and control sample has been sequenced on a Illumina HiSeq2000 instrument in paired-end mode. Up to three lanes per sample have been sequenced resulting in 112 Fastq files.
EGAD00001003940 | EGA
Genomicsena-DATASET-dkfz_b062-21-02-2018-14:40:33:479-591 - samples
This dataset contains whole exome sequencing data from 24 patients. The Agilent SureSelect Human All Exon 50-Mb target enrichment kit was used to capture all human exons for deep sequencing. For each patient a tumour and control sample has been sequenced on a Illumina HiSeq2000 instrument in paired-...
EGAD00001003973 | EGA
Genomics7635cfb5-4bb5-44fa-9d28-3760b584ba69 - samples
This dataset contains CTCF ChIP-sequencing data from seven samples (six tumor samples and one tumor derived cell line). Following library amplification, DNA fragments were sequenced using Illumina HiSeq 2000 paired-end sequencing resulting in 14 FASTQ files.
EGAD00001008806 | EGA
GenomicsData Access Committee of divisions B060 and B062, German Cancer Research Center (DKFZ)
Data Access Committee EGAC00001001626
EGAC00001001626 | EGA
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