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MetabolomicsAlterations in the metabolic footprint induced by Mayaro virus infection in cell culture
This study focuses metabolic footprinting of Vero cells infected by Mayaro virus. Nuclear magnetic resonance combined with multivariate analytical methods and tools of pattern recognition shows that metabolic changes can be attributed to the effect of Mayaro virus infection. Vero cells infected by M...
2021-10-28 | MTBLS639 | MetaboLights
GenomicsSindbis virus strain:MRE16
Sindbis virus strain:MRE16 Raw sequence reads
PRJNA699225 | ENA
GenomicsSindbis virus
Sindbis virus Raw sequence reads
PRJNA361123 | ENA
GenomicsCulex pipiens strain:Sindbis virus
Culex pipiens strain:Sindbis virus Raw sequence reads
PRJNA350497 | ENA
GenomicsSindbis virus
Sindbis virus structural polyprotein -1 PRF deep mutational scan
PRJNA720960 | ENA
TranscriptomicsIdentification of RNase L-dependent, 3M-bM-^@M-2-end-modified, viral small RNAs in Sindbis virus-infected mammalian cells
Small RNAs play a critical role in host-pathogen interaction. In insects, for instance, small RNA-mediated silencing or RNA interference (RNAi) represents the main antiviral defense system. However, the antiviral role of RNAi has not been clearly proven in higher vertebrates. On the contrary, it is ...
ORGANISM(S): Chlorocebus aethiops 
2013-11-19 | E-GEOD-48831 | biostudies-arrayexpress
ProteomicsThe effects of Sindbis viral vectors on neuronal function
Viral vectors are attractive tools to express genes in neurons. Transduction of neurons with a recombinant, replication-deficient Sindbis viral vector is a method of choice for studying the effects of short-term protein overexpression on neuronal function. However, to which extent Sindbis by itself ...
ORGANISM(S): Mus musculus (Mouse) 
2019-08-26 | PXD013634 | Pride
Triple tof Proteomics Hippocampus Mouse Sindbis virus 
TranscriptomicsTranscription profiling of Aedes infected with alphavirus, Sindbis (MRE16 Malaysian strain)
The midgut of hematophagous insects is the initial site of infection by arthropod-borne viruses (arboviruses) and plays a crucial role in vector competence. To further understand processes that occur in the midgut in response to infection by an arbovirus, DNA microarrays were used to analyze gene ex...
ORGANISM(S): Aedes aegypti 
2005-08-01 | E-MEXP-381 | biostudies-arrayexpress
ProteomicsSystem-wide profiling of protein-RNA interactions in sindbis infected cells reveals host regulators of infection
RNA viruses rely on cellular RNA-binding proteins (RBPs) to infect the host cell. However, the repertoire of the cellular RBPs exploited by viruses is largely unknown. Using the ‘RNA interactome capture’ method, we profiled in a proteome-wide scale the RBP-RNA interactions occurring during sindbis v...
ORGANISM(S): Homo sapiens (Human) Sindbis virus 
2019-02-28 | PXD009789 | Pride
Human Lc-msms Sindbis virus 
ProteomicsDEAD box RNA helicase 5 and 17 are novel host factors for Sindbis virus infection.
The DEAD-box ATP-dependent RNA helicases DDX5 and DDX17 play a role in many aspects of cellular RNA biology, including metabolism, translation, splicing, transcription regulation, ribosome biogenesis, mRNA nuclear export, and miRNA processing. Moreover, both RNA helicases were found to either promot...
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD044867 | Pride
Sindbis virus Ddx5 Helicase Ddx17 Rna 
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