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UnknownSynthetic long non-coding RNAs [SINEUPs] rescue defective gene expression in vivo.
Not available
S-EPMC4893607 | biostudies-literature
UnknownSINEUPs are modular antisense long non-coding RNAs that increase synthesis of target proteins in cells.
Not available
S-EPMC4429562 | biostudies-literature
UnknownIdentification of functional features of synthetic SINEUPs, antisense lncRNAs that specifically enhance protein translation.
Not available
S-EPMC5802440 | biostudies-literature
UnknownIdentification of antisense long noncoding RNAs that function as SINEUPs in human cells.
Not available
S-EPMC5028707 | biostudies-literature
ProteomicsInternal Ribosome Entry Site RNAs act in trans through an antisense sequence
SINEUPs are antisense long non-coding RNAs (lncRNAs) that increase translation of overlapping mRNAs through the activity of two domains: an embedded SINEB2 sequence UP-regulates translation (Effector Domain) while the antisense region provides target specificity (Binding Domain). In this study, we ...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD028571 | Pride
Proteomics Circ5533 Pxk Binding domain Sineups 
UnknownSINEUP non-coding RNAs rescue defective frataxin expression and activity in a cellular model of Friedreich's Ataxia.
Not available
S-EPMC6847766 | biostudies-literature
UnknownInternal ribosome entry sites enhance translation in trans in antisense non-coding SINEUP and circular RNAs.
Not available
S-EPMC12359042 | biostudies-literature
OtherIn-cell structure analysis of antisense Gadd45α SINEB2-a deletion mutants
SINEUPs are SINE repeat element containig long non-coding RNAs (lncRNAs)which positively regulate target mRNA translation at post-transcription level. SINE RNA region is crucial for SINEUP function. To analyze the effect of sequence deletion on RNA secondary structure of SINEB2 RNA derived from mous...
ORGANISM(S): Homo sapiens 
2023-09-19 | GSE243220 | GEO
UnknownStructural determinants of the SINE B2 element embedded in the long non-coding RNA activator of translation AS Uchl1.
Not available
S-EPMC5816658 | biostudies-literature
OtherIn-cell RNA secondary structure analysis of functional SINE transcripts
SINEUPs are long non-coding RNAs which contain a functionally crucial SINE repeat element and positively regulate target mRNA translation at post-transcription level. To study secondary (2D) structure of these functional SINE-derived RNAs, various SINEUP-GFP plasmids containing different mouse SINEB...
ORGANISM(S): Homo sapiens 
2023-02-06 | GSE224534 | GEO
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