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MetabolomicsA Multi-omics Longitudinal Study Reveals Alteration of the Leukocyte Activation Pathway in COVID-19 Patients
Severe coronavirus disease 2019 (COVID-19) infection may lead to lung injury, multi-organ failure, and eventually death. Cytokine storm due to excess cytokine production has been associated with fatality in severe infections. However, the specific molecular signatures associated with the elevated im...
2022-01-18 | MTBLS2469 | MetaboLights
ProteomicsTOMATO SEEDLING LIGHT INDUCED PROTEOMICS ALTERATON
We use quantitative discovery proteomics along with metabolomics to unravel the role of Phytochrome A in regulating central metabolism.
ORGANISM(S): Solanum lycopersicum 
2021-09-10 | PXD023589 | Pride
Phytochrome a Seedling Light Itraq Tomato 
UnknownOverexpression of differentially expressed AhCytb6 gene during plant-microbe interaction improves tolerance to N2 deficit and salt stress in transgenic tobacco.
Not available
S-EPMC8239016 | biostudies-literature
ProteomicsProteomic Investigation Reveals Dominant Alterations of Neutrophil Degranulation and mRNA Translation Pathways in COVID-19 Patients
The altered molecular proteins and pathways in response to COVID-19 infection are still unclear. Here, we performed a comprehensive proteomics-based investigation of of nasopharyngeal swab samples from COVID-19 patients to identify viral and host peptides by employing simple extraction strategies an...
ORGANISM(S): Homo sapiens (Human) 
2021-02-15 | PXD023016 | Pride
Covid-19 Human Nasopharyngeal swab Sars-cov-2 Mass spectrometry Proteomics 
ProteomicsViral fallout: Semen proteome reveals COVID-19 dysregulates several biological processes linked to male reproductive function
The current global outbreak of COVID-19 has significantly impacted several organ systems. Male reproductive organs are among the potential targets of SARS-CoV-2 infection owing to the presence of abundant viral receptors; ACE2 and TMPRSS2 in the testis. However, the questions pertaining to the long...
ORGANISM(S): Homo sapiens (Human) 
2022-04-04 | PXD026703 | Pride
Sars-cov-2 Semen Male reproductive function Proteomics Covid-19 
ProteomicsProteomic Investigation Reveals Dominant Alterations of Neutrophil Degranulation and mRNA Translation Pathways in COVID-19 Patients
With the increasing cases of SARS-CoV2 mediated COVID-19, which has taken the form of a savagely spreading pandemic, quick and effective detection and diagnosis is the need of the hour. While clinical testing is aimed at identifying the positive vs. negative cases, there are also enormous challenges...
ORGANISM(S): Homo sapiens (Human) 
2021-02-09 | PXD020580 | Pride
Covid-19 Human Nasopharyngeal swab Sars-cov-2 Mass spectrometry Proteomics Lc-ms/ms 
ProteomicsMass-spectrometry based plasma proteomics identifies biomarkers for the detection of COVID-19 progression
COVID-19 manifests itself in an array of symptoms. While most patients experience very mild-to-moderate symptoms, around one in five patients develop pneumonia coupled with severe respiratory distress. These patients require treatment in the intensive care units (ICU), however, most of the times, it...
ORGANISM(S): Homo sapiens (Human) 
2021-04-01 | PXD022296 | Pride
Sars-cov2 Human Plasma Proteomics Covid-19 Lc-ms/ms 
UnknownWeak yet directional: supramolecular interactions of thiols unravelled by quantum crystallography.
Not available
S-EPMC12355400 | biostudies-literature
ProteomicsA longitudinal study of COVID-19 patients using proteomics approach
SARS-CoV-2, a highly contagious and infectious virus is responsible for causing this COVID-19 pandemic, which has a substantial impact on global health and economy. The spectrum of clinical manifestations of COVID-19 ranges from mild or non-severe state to severe life-threatening condition in some g...
ORGANISM(S): Homo sapiens (Human) 
2021-05-27 | PXD023521 | Pride
Sars-cov2 Severe vs non-severe Human Plasma Proteomics Covid-19 Lc-ms/ms 
ProteomicsSemen proteome analysis comparing the persistent effects of different SARS-COV-2 variants on male reproductive system in recovered men
After the initial COVID-19 wave, India experienced a second COVID-19 wave in March 2021, which was driven by the delta variant. By January 2021, India has also begun its vaccine campaign. Therefore, semen samples from recovered patients who were infected during the two waves of COVID-19 in India wer...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD041904 | Pride
Sars-cov-2 Proteomics Covid-19 Infertility Male reproductive system 
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