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ProteomicsTranslational repression of NMD targets by GIGYF2 and EIF4E2
Translation of messenger RNAs (mRNAs) with premature translation termination codons produces truncated proteins with potentially deleterious effects. This is prevented by nonsense-mediated mRNA decay (NMD) of these mRNAs. NMD is triggered by ribosomes terminating upstream of a splice site marked by ...
ORGANISM(S): Homo sapiens (Human) 
2021-10-12 | PXD027479 | Pride
Nmd Eif4e2 Gigyf2 Translation 
ProteomicsInteractome of GIGYF2 and EIF4E2 with and without SMG1i treatement
Translation of messenger RNAs (mRNAs) with premature translation termination codons produces truncated proteins with potentially deleterious effects. This is prevented by nonsense-mediated mRNA decay (NMD) of these mRNAs. NMD is triggered by ribosomes terminating upstream of a splice site marked by ...
ORGANISM(S): Homo sapiens (Human) 
2021-10-12 | PXD027487 | Pride
Nmd Smg1i Gigyf2. eif4e2 
ProteomicsThe ribotoxic stress response drives UV-mediated cell death.
Supporting raw MS data for paper (doi: 10.1016/j.cell.2024.05.018) by Sinha N.K. et al, titled "The ribotoxic stress response drives UV-mediated cell death". Index of MS files and labels Table S1 - HaCaT Timecourse. 1-1 - Proteome (AO3604-3627 | Unimod:35; 2016; 4 | 126 -UT_01; 127n - UT_02; 12...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-07-25 | MSV000092521 | MassIVE
ProteomicsEDF1 coordinates cellular responses to ribosome collisions
Raw mass spectrometry data associated with the following paper: EDF1 coordinates cellular responses to ribosome collisions. Related to Figure 2, Figure 2-figure supplement 1 and Figure 2-source data 1. Files detail: Monosome (6 BPRP fractions - labeled AO3104-3109); Polysome (6 BPRP fractions - labe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-15 | MSV000085419 | MassIVE
ProteomicsEDF1 coordinates cellular responses to ribosome collisions
Raw mass spectrometry data associated with the following paper: EDF1 coordinates cellular responses to ribosome collisions. Related to Figure 2-figure supplement 2A and Figure 2-source data 2. Files detail: See attached Search Engine File named "Sample info and Maxquant summary"
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-15 | MSV000085422 | MassIVE
ProteomicsEDF1 coordinates cellular responses to ribosome collisions
Raw mass spectrometry data associated with the following paper: EDF1 coordinates cellular responses to ribosome collisions. Related to Figure 5B, Figure 5-figure supplement 1B-1C and Figure 5-source data 2. Files detail: See attached Search Engine file named "Sample info and Maxquant summary"
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-15 | MSV000085421 | MassIVE
ProteomicsEDF1 coordinates cellular responses to ribosome collisions
Raw mass spectrometry data associated with the following paper: EDF1 coordinates cellular responses to ribosome collisions. Related to Figure 6B-6C, Figure 6-figure supplement 1 and Figure 6-source data 1. Files detail: Light-Polysome (12 BPRP fractions - labeled AO3310-3321); Heavy-Polysome (12 BPR...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-15 | MSV000085420 | MassIVE
ProteomicsEDF1 coordinates cellular responses to ribosome collisions
Raw mass spectrometry data associated with the following paper: EDF1 coordinates cellular responses to ribosome collisions. Related to Figure 2H and Figure 2-figure supplement 2F.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-15 | MSV000085425 | MassIVE
ProteomicsEDF1 coordinates cellular responses to ribosome collisions
Raw mass spectrometry data associated with the following paper: EDF1 coordinates cellular responses to ribosome collisions. Related to Figure 5A and Figure 5-source data 1. Files detail: See attached Search Engine file named "Sample info and Maxquant summary"
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-15 | MSV000085424 | MassIVE
ProteomicsEDF1 coordinates cellular responses to ribosome collisions
Raw mass spectrometry data associated with the following paper: EDF1 coordinates cellular responses to ribosome collisions. Related to Figure 1, Figure 1-figure supplement 1 and Figure 1-source data 1. Files detail: 11 sucrose gradient fractions (Fr1-11 respectively labeled AO3038-3048)
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-15 | MSV000085423 | MassIVE
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