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MetabolomicsFirst-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver mass. Therapies to restore hepatocyte regeneration are lacking, making liver transplantation...

2024-09-23 | MTBLS9434 | MetaboLights
TranscriptomicsKnockout mice reveal key roles for claudin-18 in alveolar fluid homeostasis.
Claudin proteins are major constituents of epithelial and endothelial tight junctions (TJ), where they serve as regulators of paracellular permeability to ions and solutes. Claudin-18, a member of the large claudin family, is highly expressed in lung epithelium. To elucidate the role of claudin-18 i...
ORGANISM(S): Mus musculus 
2014-04-06 | E-GEOD-48443 | biostudies-arrayexpress
TranscriptomicsExpression data from human colonic biopsy sample
Gene expression profile based classification of colonic diseases are suitable for identification of diagnostic mRNA expression patterns which can establish the basis of a new molecular biological diagnostic method Keywords: whole genomic expression Total RNA was extracted from colonic biosy samples ...
ORGANISM(S): Homo sapiens 
2009-01-29 | E-GEOD-10714 | biostudies-arrayexpress
TranscriptomicsExpression data from normal and CRC human peripheral blood samples
The whole-genome oligonucleotide microarray analysis of peripheral blood samples can contribute to the determination of distant blood markers of local pathophysiological alterations in colorectal diseases. These markers can lead to alternative screening procedures. Keywords: whole genomic expression...
ORGANISM(S): Homo sapiens 
2009-01-29 | E-GEOD-10715 | biostudies-arrayexpress
TranscriptomicsExpression data from NS398-treated and control HT29 colon adenocarcinoma cell line samples
The whole-genome oligonucleotide microarray analysis of NS398-treated HT29 colon adenocarcinoma cells samples can give an insight into global molecular background of selective COX2 inhibitor administration in order to find other target molecules and pathways influenced by NS398 selective COX2 inhib...
ORGANISM(S): Homo sapiens 
2010-03-16 | E-GEOD-15799 | biostudies-arrayexpress
UnknownAssessment of anthropogenic activities impact based on metals in soil and tree leaves along roadside in Bangladesh.
Not available
S-EPMC11865477 | biostudies-literature
UnknownAutoimmunity and Carcinogenesis: Their Relationship under the Umbrella of Autophagy.
Not available
S-EPMC10135912 | biostudies-literature
UnknownBackground and Clinical Features of a Unique and Mysterious Autoinflammatory Disease, Schnitzler Syndrome.
Not available
S-EPMC11765222 | biostudies-literature
UnknownCAR-Based Therapy for Autoimmune Diseases: A Novel Powerful Option.
Not available
S-EPMC10252902 | biostudies-literature
TranscriptomicsExpression data from human colonic epithelial cells normal (N), adenoma (AD) or colorectal cancer (CRC) tissues
The whole-genome oligonucleotide microarray analysis of laser microdissected human colonic epithelial cells can contribute to determination of disease-specific expression alterations in colonic epithelial cells and to localize the origin the expression changes measured in whole biopsy samples. Key...
ORGANISM(S): Homo sapiens 
2010-03-15 | E-GEOD-15960 | biostudies-arrayexpress
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