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TranscriptomicsAnalysis of growth-phase regulated genes in Streptococcus agalactiae by global transcript profiling
We determined dynamic behavior of S. agalactiae transcriptome during growth in THY medium and detected growth phase regulated genes Three independent cultures (three biological replicates) of S. agalactiae NEM316 strain in rich laboratory medium were sampled at mid log, late log early and late stati...
ORGANISM(S): Streptococcus agalactiae 
2010-05-19 | E-GEOD-12238 | biostudies-arrayexpress
TranscriptomicsInduction of adaptive changes in the Streptococcus agalactiae transcriptome by human blood
In the present investigation, we conducted a bacterial transcriptome dynamics analysis during GBS incubation with human blood. We observed a large modification in the expression of genes involved in transcriptional regulation and in the metabolism of carbohydrates, purins/pyrimidins and inorganic io...
ORGANISM(S): Streptococcus agalactiae 
2008-10-31 | E-GEOD-11705 | biostudies-arrayexpress
TranscriptomicsRemodeling of the Streptococcus agalactiae transcriptome in response to growth temperature
To understand the extent to which GBS modify gene expression in response to temperatures encountered in the various hosts, we conducted a whole genome transcriptome analysis of organisms grown at 30°C and 40°C. We identified extensive transcriptome remodeling at various stages of growth, especially ...
ORGANISM(S): Streptococcus agalactiae 
2008-09-01 | E-GEOD-11666 | biostudies-arrayexpress
TranscriptomicsDifferential Streptococcus agalactiae gene expression in human blood according to the blood donors
In the present investigation, we conducted a bacterial transcriptome dynamics analysis during GBS incubation with human blood. We observed large modification in the expression of numerous genes, but GBS transcriptome was different with the blood of one donor. More genes were up-regulated and less do...
ORGANISM(S): Streptococcus agalactiae 
2009-06-01 | E-GEOD-12201 | biostudies-arrayexpress
TranscriptomicsTranscriptome adaptation of group B Streptococcus to growth in human amniotic fluid
We have discovered that GBS significantly remodels its transcriptome in response to exposure to human amniotic fluid. A large number of the affected genes are of unknown function, which means that much remains to be learned about the full influence of amniotic fluid on GBS. The majority of the obse...
ORGANISM(S): Streptococcus agalactiae 
2010-05-18 | E-GEOD-14456 | biostudies-arrayexpress
TranscriptomicsDetermination of transcriptome of SptR in group A Streptococcus during growth in human saliva
The molecular genetic mechanisms used by bacteria to persist in humans are poorly understood. Group A Streptococcus (GAS) causes the majority of bacterial pharyngitis cases in humans and is prone to persistently inhabit the upper respiratory tract. To gain information about how GAS survives in and i...
ORGANISM(S): Streptococcus sp. 'group A' 
2010-05-19 | E-GEOD-16124 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression in MGAS315 and its isogenc mtsR mutant
RATIONALE: mtsR is a regulator of genes involved in ion aquisition in S. pyogenes that has been suggested to be involved in development of invasive infections. We wanted to identify mtsR regulon. EXPERIMENT: We compared global gene expression in wild type strain MGAS315 with expression in its isogen...
ORGANISM(S): Streptococcus pyogenes 
2010-05-06 | E-GEOD-10252 | biostudies-arrayexpress
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