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ProteomicsCharacterization of fibrosis and senescence of human omental peritoneal mesothelial cells
Primary human omental mesothelial cells from multiple donors in a young (=normal) phase and senescent phase were treated with or without TGF-ß to induce fibrosis. Senescence was induced by up to 9 passages and confirmed by stopped cell division and positive senescence-associated β-galactosidase stai...
ORGANISM(S): Homo sapiens (Human) 
2024-06-22 | PXD048090 | Pride
Fibrosis Peritoneal dialysis Senescence 
ProteomicsMHC class I-mediated antigen presentation is independent of calreticulin
TMT-MS analysis of the proteome in whole cell lysates from primary murine neutrophil granulocytes and CD8+ T cells obtained from mice carrying a calreticulin knock out or oncogenic mutation (CALRdel52)
ORGANISM(S): Mus musculus (Mouse) 
2025-11-17 | PXD062085 | Pride
Calreticulin Knock out Cd8+ t cells Tandem mass tag mass spectrometry Mutated Mouse Tmt-ms Myeloproliferative neoplasm Neutrophil granulocytes Calrdel52 
ProteomicsTMTpro-SP3-LC-MS analysis of peritoneal dialysis effluent of a phase 2 randomized clinical trial
Peritoneal dialysis (PD) is a modality of renal replacement therapy in which the high volumes of available PD effluent (PDE) represents a rich source of biomarkers for monitoring disease and therapy. Although this information could help guiding the management of PD patients, little is known about th...
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD050859 | Pride
Tmt Peritoneal dialysis 
TranscriptomicsCXCL4 induces a unique transcriptome in monocyte-derived macrophages
Human blood monocytes were differentiated over six days with either 100 ng/ml M-CSF or 1 umol/l CXCL4 In atherosclerotic arteries, blood monocytes differentiate to macrophages in the presence of growth factors like macrophage colony-stimulation factor (MCSF) and chemokines like platelet factor 4 (CX...
ORGANISM(S): Homo sapiens 
2010-03-07 | E-GEOD-20484 | biostudies-arrayexpress
ProteomicsDeep analysis of FCS used in cell culture experiment
roteome analysis of commercially available foetal calf serum (FCS) for background correction. Commercially available FCS was depleted of high abundant and enriched for low abundant proteins with commercially available equalizer beads (BioRad) to create a background list of potential contaminates.
ORGANISM(S): Bos taurus (Bovine) 
2025-11-17 | PXD062778 | Pride
Fetal calf serum (fcs) 
TranscriptomicsTranscription profiling of rat insulinoma (INS-1 derived) cells grown in lipid culture
This experiment was designed to study the effects of lipid culture on INS-1 derived glucose-responsive 832/13 cells. After 48-hr culture with lipids, a dramatic decrease in glucose-responsiveness is observed. In order to detect some earlier changes, RNA was also collected at earlier time points (1...
ORGANISM(S): Rattus norvegicus 
2007-09-11 | E-CBIL-34 | biostudies-arrayexpress
TranscriptomicsTranscriptomics analysis of skeletal muscle in humans with heart failure
Heart failure is a multisystem syndrome caused by structural and functional defects in multiple tissues. The study aims to identify differentially regulated genes in skeletal muscle of heart failure patients. Here, we obtained biopsies from the pectoralis major muscle and performed RNA sequencing to...
ORGANISM(S): Homo sapiens 
2020-09-07 | E-MTAB-8531 | biostudies-arrayexpress
ProteomicsAmylase/trypsin-inhibitor content and inhibitory activity of German common wheat landraces and modern varieties do not differ
Amylase/trypsin-inhibitors (ATIs) are triggers for wheat-related disorders like baker’s asthma and nonceliac wheat sensitivity. With the rise ofwheat-related disordersamong the population, the hypothesis that breeding may have resulted in changes in the protein composition of wheat was put forward. ...
ORGANISM(S): Triticum Aestivum 
PXD060528 | panorama
UnknownPerformance-based clinical tests of balance and muscle strength used in young seniors: a systematic literature review.
Not available
S-EPMC6327480 | biostudies-literature
TranscriptomicsTranscription profiling of Arabidopsis wild-type, thylakoidal ascorbate peroxidase overexpressor (over tAPX, line 14/2), flu mutant and flu plants overexpressing thylakoidal ascorbate peroxidase
We used the flu mutant of Arabidopsis and a transgenic line that overexpresses the thylakoid-bound ascorbate peroxidase (tAPX) to address the interactions between different reactive oxygen species (ROS) signaling pathways. The conditional flu mutant of Arabidopsis accumulates excess protochlorophyll...
ORGANISM(S): Arabidopsis thaliana 
2008-04-05 | E-GEOD-10812 | biostudies-arrayexpress
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