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ProteomicsExploiting induced pluripotent stem cell-derived macrophages to unravel host factors influencing Chlamydia trachomatis pathogenesis
Chlamydia trachomatis remains a leading cause of bacterial sexually transmitted infections and preventable blindness worldwide. There are, however, limited in vitro models to study the role of host genetics in the response of macrophages to this obligate human pathogen. Here, we describe an approach...
ORGANISM(S): Chlamydia trachomatis Homo sapiens (Human) 
2018-02-14 | PXD005858 | Pride
Tmt Chlamydia Ips cells Lc-msms 
UnknownMiR-25 regulates Wwp2 and Fbxw7 and promotes reprogramming of mouse fibroblast cells to iPSCs.
Not available
S-EPMC3422229 | biostudies-literature
UnknownCRISPR-Cas9 enables conditional mutagenesis of challenging loci.
Not available
S-EPMC5007477 | biostudies-literature
UnknownExploiting induced pluripotent stem cell-derived macrophages to unravel host factors influencing Chlamydia trachomatis pathogenesis.
Not available
S-EPMC5414054 | biostudies-literature
TranscriptomicsThe polyA+ transcriptomes of mouse embryonic stem cells and their derived neural precursors from strand-specific RNA-Seq
We have examined the nuclear (nuc) and cytoplasmic (cyt) polyA+ transcriptomes of undifferentiated mouse embryonic stem cells (un) and cells differentiated to neural precursors (d5) using strand-specific RNA-Seq. The 46C mouse embryonic stem cell line was used for this study. Two cell types were exa...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-38990 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression profiles during differentiation of mouse embryonic stem cells to macrophages
This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/We established protocols to generate monocytes and ...
ORGANISM(S): Mus musculus 
2013-05-28 | E-ERAD-132 | biostudies-arrayexpress
UnknownHyperexcitability and Pharmacological Responsiveness of Cortical Neurons Derived from Human iPSCs Carrying Epilepsy-Associated Sodium Channel Nav1.2-L1342P Genetic Variant.
Not available
S-EPMC8660047 | biostudies-literature
UnknownHuman microglia in brain assembloids display region-specific diversity and respond to hyperexcitable neurons carrying <i>SCN2A</i> mutation: Microglial diversity and response in assembloids.
Not available
S-EPMC12157492 | biostudies-literature
UnknownHuman microglia in brain assembloids display region-specific diversity and respond to hyperexcitable neurons carrying <i>SCN2A</i> mutation.
Not available
S-EPMC12915608 | biostudies-literature
UnknownA systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage.
Not available
S-EPMC7611045 | biostudies-literature
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