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ProteomicsQuantitative proteomics of the infectious and replicative forms of Chlamydia trachomatis L2
The obligate intracellular developmental cycle of Chlamydia trachomatis presents significant challenges in defining its proteome. In this study we have applied quantitative proteomics to both the intracellular reticulate body (RB) and the extracellular elementary body (EB) from C. trachomatis. We...
ORGANISM(S): Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) 
2016-06-28 | PXD003025 | Pride
Reticulate body Elementary body L2 Chlamydia trachomatis 
ProteomicsLarge-scale HDMSE mapping of the normal sputum proteome
Severe asthma is a collection of disease entities with varying pathophysiological characteristics that result in symptoms of cough, wheeze and breathlessness, with frequent exacerbations. To address the problem of phenotypic difference and heterogeneity, the Unbiased Biomarkers for the Prediction of...
ORGANISM(S): Homo sapiens (Human) 
2018-05-14 | PXD005949 | Pride
Label free Data independent Human Sputum 
ProteomicsAn integrated model system to study biofilm-associated adaptation to antimicrobials and resistance evolution in Pseudomonas aeruginosa MPAO1
Using an integrated model system for reproducible growth of biofilms, a JPIAMR-funded consortium of researchers* studied the expressed proteome of P. aeruginosa strain MPAO1 under i) planktonic growth, and ii) biofilm formation conditions. The model system included, as a first step, the sequencing a...
ORGANISM(S): Pseudomonas aeruginosa 
2021-09-09 | PXD017122 | Pride
Comparative genomics Strain mpao1 Planktonic Biofilm Flow chamber Colistin Proteogenomics Shotgun proteomics Transposon sequencing Antibiotic resistance related proteins Genome sequencing Antimicrobials P. aeruginosa 
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