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MetabolomicsRegional Immunological and Microbial Characterization of Peyer's Patches in the Small Intestine of Bactrian Camels

Background: Our earlier research showed that Bactrian camels have a unique lymph aggregation structure that is similar to ileal Peyer's patches (PPs) and plays a role in the mucosal immunology of the digestive tract. However, Bactrian camels exhibit PPs not only in the ileum but also in all segme...

2024-11-11 | MTBLS10376 | MetaboLights
MetabolomicsSmall auxin-up RNA promotes GmMYB176 gene transcription to modulate soybean isoflavone content

Isoflavones have been widely studied because of their potential health benefits, including antioxidant, anti-inflammatory, and anticancer properties. Soybeans (Glycine max (L.) Merr) are an effective source of natural isoflavones in humans. Therefore, it is important to cultivate varieties showin...

2025-06-23 | MTBLS12627 | MetaboLights
MetabolomicsDifferential analysis of physicochemical properties and small molecule metabolites in glutinous and non-glutinous sorghum
In this study, using 2 glutinous sorghum and 2 non-glutinous sorghum as research objects, and their differences in grain appearance color, peel thickness, starch structure and small molecule metabolites were analyzed and compared. The results showed that the grain of 2 glutinous sorghum was red, and...
2024-11-28 | MTBLS11382 | MetaboLights
TranscriptomicsTMV-derived Small RNAs Reveals Role for Arabidopsis thaliana RNA-dependent RNA Polymerases in Viral siRNA Biogenesis
Using a crucifer-infecting strain of Tobacco Mosaic Virus (TMV-Cg) and Arabidopsis thaliana as a model system, we analyzed the viral small RNA profile in wild-type plants as well as rdr mutants by applying small RNA deep sequencing technology. Over 100,000 TMV-Cg-specific small RNA reads, mostly of...
ORGANISM(S): Youcai mosaic virus 
2009-03-24 | E-GEOD-12918 | biostudies-arrayexpress
TranscriptomicsP6 Mouse Sertoli Cell Small RNA seq
This study annotates the NGS reads in a Sertoli cell sncRNA library. In addition to known sncRNAs, we also identified numerous novel sncRNAs expressed by Sertoli cells. Our data suggest that the Sertoli cell sncRNA transcriptome predominantly consists of miRNAs, piRNA-like RNAs, tRNAs and snoRNAs....
ORGANISM(S): Mus musculus 
2012-09-08 | E-GEOD-40692 | biostudies-arrayexpress
TranscriptomicsThe small RNA repertoire of Dictyostelium discoideum
Small RNAs play crucial roles in regulation of gene expression in many eukaryotes. Here, we report the cloning and characterization of 18-26 nt RNAs in the social amoeba Dictyostelium discoideum. This survey uncovered developmentally regulated microRNA candidates whose biogenesis, at least in one ca...
ORGANISM(S): Dictyostelium discoideum 
2007-10-16 | E-GEOD-8755 | biostudies-arrayexpress
MetabolomicsApoptosis-inducing effects of aqueous extract of Eleutherococcus senticosus on non-small cell lung cancer cell proliferation

Non-small cell lung cancer is a malignant tumor with high morbidity and mortality worldwide. Eleutherococcus senticosus can induce apoptosis in non-small cell lung cancer cells, but the mechanism remains unclear. This study aimed to elucidate the role of Eleutherococcus senticosus in inducing apo...

2025-05-12 | MTBLS10545 | MetaboLights
TranscriptomicsNovel microRNAs uncovered by deep sequencing of small RNA transcriptomes in T. aestivum and B. distachyon
The small RNA transcriptomes of bread wheat (Triticum aestivum L.) and its emerging model (Brachypodium distachyon (L.) Beauv) were obtained by using deep sequencing technology. Small RNA compositions were analyzed in these two species. In addition to 70 conserved microRNAs (miRNA) from 25 families,...
ORGANISM(S): Triticum aestivum 
2009-06-07 | E-GEOD-16177 | biostudies-arrayexpress
GenomicsMuTHER adipose tissue small RNA expression
We investigate the naturally occurring variation of small RNA expression in conjunction with genetic and gene expression variation. We shall assess the variation in subabdominal fat tissue small RNA levels in 168 unrelated MuTHER individuals. Using gene expression data from the same samples, we can ...
EGAS00001000212 | EGA
TranscriptomicsCharacterization of unique small RNA populations from rice grain
Small RNAs (~20 to 24 nucleotides) function as naturally occurring molecules critical in developmental pathways in plants and animals. Here we analyze small RNA populations from mature rice grain and seedlings by pyrosequencing. Using a clustering algorithm to locate regions producing small RNAs, w...
ORGANISM(S): Oryza sativa 
2008-11-24 | E-GEOD-13152 | biostudies-arrayexpress
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