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TranscriptomicsTranscription profiling by array of mouse tissues from different mouse strains to investigate the effects of copy number variation on gene expression
Copy number variation (CNV) of DNA segments has recently been identified as a major source of genetic diversity, but a more comprehensive understanding of the extent and phenotypic effect of this type of variation is only beginning to emerge. In this study we generated genome-wide expression data fr...
ORGANISM(S): Mus musculus 
2009-02-28 | E-GEOD-10744 | biostudies-arrayexpress
TranscriptomicsCis-encoded sRNAs repress expression of polysaccharide utilization loci in Bacteroides fragilis 638R
The phylum Bacteroidetes is a major component of the human gut microbiota which has a broad impact on the development and physiology of its host, and a potential role in a wide range of disease syndromes1-3. The predominance of Bacteroidetes and the genus Bacteroides in the distal gut is due in larg...
ORGANISM(S): Bacteroides fragilis 638R 
2016-07-22 | E-GEOD-73107 | biostudies-arrayexpress
TranscriptomicsRearrangement of CRLF2 in B-progenitor and Down syndrome associated acute lymphoblastic leukemia
Chromosomal aneuploidy and translocations are hallmarks of acute lymphoblastic leukemia (ALL), but many patients lack a recurring chromosomal alteration. Here we report a recurring interstitial deletion of the pseudoautosomal region 1 of chromosomes X and Y in B-progenitor ALL that results in the ex...
ORGANISM(S): Homo sapiens 
2009-10-18 | E-GEOD-16724 | biostudies-arrayexpress
UnknownSurvival, Durable Response, and Long-Term Safety in Patients With Previously Treated Advanced Renal Cell Carcinoma Receiving Nivolumab.
Not available
S-EPMC4517051 | biostudies-literature
MetabolomicsUntargeted Metabolomics Reveals Molecular Effects of Ketogenic Diet on Healthy and Tumor Xenograft Mouse Models
The application of ketogenic diet (KD) (high fat/low carbohydrate/adequate protein) as an auxiliary cancer therapy is a field of growing attention. KD provides sufficient energy supply for healthy cells, while possibly impairing energy production in highly glycolytic tumor cells. Moreover, KD regula...
2019-10-08 | MTBLS1066 | MetaboLights
UnknownApplying Educational Theory and Best Practices to Solve Common Challenges of Simulation-based Procedural Training in Emergency Medicine.
Not available
S-EPMC7011411 | biostudies-literature
TranscriptomicsTranscription profiling time series toxicogenomic profiles in CD-1 mice after nontoxic and nonlethal hepatotoxic paracetamol administration
Effect of vehicle vs non-toxic and toxic paracetamol (151mg/kg and 529mg/kg) doses on the gene expression profile at 1, 4 and 24h in murine liver.
ORGANISM(S): Mus musculus 
2004-02-20 | E-MEXP-82 | biostudies-arrayexpress
UnknownAn ASER AI/ML expert panel formative user research study for an interpretable interactive splenic AAST grading graphical user interface prototype.
Not available
S-EPMC11257379 | biostudies-literature
TranscriptomicsAnalysis of the Haloferax volcanii Transcriptome
In this study the transcriptome of Haloferax volcanii DS70 (Wendoloski D, Ferrer C, Dyall-Smith ML. Microbiology. 2001, 147: 959-64), grown under of a variety of conditions, was mapped using a custom genome-wide tiled array consisting of 25 nt probes spaced in 35 nt windows. H. volcanii is a faculta...
ORGANISM(S): Haloferax volcanii 
2010-09-08 | E-GEOD-18066 | biostudies-arrayexpress
TranscriptomicsThe transcriptome of the medullary area postrema: The thirsty rat, the hungry rat and the hypertensive rat
The area postrema (AP) is a sensory circumventricular organ characterised by extensive fenestrated vasculature and neurons which are capable of detecting circulating signals of osmotic, cardiovascular, immune and metabolic status. The AP can communicate these messages via efferent projections to bra...
ORGANISM(S): Rattus norvegicus 
2011-01-22 | E-GEOD-26660 | biostudies-arrayexpress
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