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TranscriptomicsSingle-cell 5' Gene Expression and V(D)J Amplification (10X Genomics) of splenic CD4+ T cells from Plasmodium chabaudi infected mice
To associate gene expression profiles with specific features of the splenic CD4+ T-cell repertoire generated during a blood stage P. chabaudi infection, we obtained both transcriptomic and T-cell receptor data from 2 infected mice at 7 days following infection.
ORGANISM(S): Mus musculus 
2020-11-13 | E-MTAB-9691 | biostudies-arrayexpress
UnknownEpacadostat Plus Pembrolizumab in Patients With Advanced Solid Tumors: Phase I Results From a Multicenter, Open-Label Phase I/II Trial (ECHO-202/KEYNOTE-037).
Not available
S-EPMC6225502 | biostudies-literature
UnknownSHARING Choices: A Pilot Study to Engage Family in Advance Care Planning of Older Adults With and Without Cognitive Impairment in the Primary Care Context.
Not available
S-EPMC8206219 | biostudies-literature
TranscriptomicsTranscriptomics analysis of skeletal muscle in humans with heart failure
Heart failure is a multisystem syndrome caused by structural and functional defects in multiple tissues. The study aims to identify differentially regulated genes in skeletal muscle of heart failure patients. Here, we obtained biopsies from the pectoralis major muscle and performed RNA sequencing to...
ORGANISM(S): Homo sapiens 
2020-09-07 | E-MTAB-8531 | biostudies-arrayexpress
GenomicsChIP-seq for RUNX1 and ETV6-RUNX1 in an induced pluripotent stem cell model of ETV6-RUNX1 pre-leukaemia
ETV6-RUNX1 is a first-hit mutation in childhood B cell precursor acute lymphoblastic leukaemia. ETV6-RUNX1 is a fusion protein which inherits the DNA-binding runt domain from RUNX1. Here we performed chromatin precipitation for native RUNX1 and ETV6-RUNX1 using RUNX1 antibodies and specifically for ...
ORGANISM(S): Homo sapiens 
2022-10-31 | E-MTAB-12208 | biostudies-arrayexpress
MetabolomicsThe impact of nutritional supplementation on sweat metabolomic content
Sweat is emerging as a prominent biosource for real-time human performance monitoring applications. Although promising, sources of variability must be identified to truly utilize sweat for biomarker applications. In this proof-of-concept study, a targeted metabolomics method was applied to sweat col...
2021-03-15 | MTBLS2427 | MetaboLights
UnknownConditional expression explains molecular evolution of social genes in a microbe.
Not available
S-EPMC6650454 | biostudies-literature
UnknownAmino Acid Substitutions in Genotype 3a Hepatitis C Virus Polymerase Protein Affect Responses to Sofosbuvir.
Not available
S-EPMC6739484 | biostudies-literature
TranscriptomicsComparative genomic hybridization by array of Streptococcus pneumoniae isolates from the Mitis group to identify pneumococcal virulance genes
Data is also available from BuG@Sbase
ORGANISM(S): Streptococcus pneumoniae 
2010-07-22 | E-BUGS-82 | biostudies-arrayexpress
ProteomicsOn-target toxicity limits the efficacy of CDK11 inhibition against cancers with 1p36 deletions
The cyclin-dependent kinase CDK11 is an understudied kinase that has been the subject of conflicting reports regarding its function in cancer. Here, we combine genetic and pharmacological approaches to demonstrate that CDK11 is a critical regulator of cancer cell survival that is required for RNA sp...
ORGANISM(S): Homo sapiens (Human) 
2026-08-07 | PXD079783 | Pride
Kinase inhibitor Ots964 Splicing Cdk11 Cell cycle 
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