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MetabolomicsUntargeted Metabolomics Reveals Molecular Effects of Ketogenic Diet on Healthy and Tumor Xenograft Mouse Models
The application of ketogenic diet (KD) (high fat/low carbohydrate/adequate protein) as an auxiliary cancer therapy is a field of growing attention. KD provides sufficient energy supply for healthy cells, while possibly impairing energy production in highly glycolytic tumor cells. Moreover, KD regula...
2019-10-08 | MTBLS1066 | MetaboLights
UnknownThe mechanisms of skeletal muscle atrophy in response to transient knockdown of the vitamin D receptor in vivo.
Not available
S-EPMC7986223 | biostudies-literature
TranscriptomicsExpression profile of splenocytes with glucose-6-phosphate isomerase (GPI) induced arthritis
To explore TNF-related genes in GPI-induced arthritis, we performed GeneChip analysis using arthritic splenocytes and control-immunized splenocytes. Among the arrayed TNFalpha-related genes, TIARP mRNA was highly expressed in arthritic splenocytes, with levels exceeding more than 20-times the contro...
ORGANISM(S): Mus musculus 
2010-03-03 | E-GEOD-17272 | biostudies-arrayexpress
UnknownClassical MHCI molecules regulate retinogeniculate refinement and limit ocular dominance plasticity.
Not available
S-EPMC2787480 | biostudies-literature
UnknownIndividual participant data (IPD)-level meta-analysis of randomised controlled trials to estimate the vitamin D dietary requirements in dark-skinned individuals resident at high latitude.
Not available
S-EPMC8857035 | biostudies-literature
GenomicsKnock-down of the methyltransferase Kmt6 reliefs H3K27me3 and results in induction of cryptic and otherwise silent secondary metabolite gene clusters in Fusarium fujikuroi
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Fusarium fujikuroi 
2016-07-04 | E-GEOD-80479 | biostudies-arrayexpress
UnknownGranzyme K activates the entire complement cascade.
Not available
S-EPMC12180478 | biostudies-literature
TranscriptomicsSingle-cell RNA sequencing data of zebrafish lymphatic and venous endothelial cells at different developmental stages (36 hpf, 48 hpf, 120 hpf (5 dpf) and 168 hpf (7 dpf))
This dataset contains single-cell RNA sequencing (scRNA-seq) profiles of zebrafish venous and lymphatic endothelial cells across development. Endothelial cells were isolated by FACS from transgenic zebrafish embryos and larvae at 36 hpf, 48 hpf, 5 dpf (120 hpf), and 7 dpf (168 hpf) using endothelial...
ORGANISM(S): Danio rerio 
2026-09-28 | E-MTAB-16797 | biostudies-arrayexpress
ProteomicsThe direct effect of mycophenolate mofetil on podocytes in nephrotoxic serum nephritis
The goal of our study was to characterize glomerulus and particularly podocyte biology during MMF treatment in an immune-triggered proteinuric glomerulopathy. Therefore, nephrotoxic serum nephritis was induced in three-week old wild-type mice. On day 3, half of the mice were treated with MMF (100 mg...
ORGANISM(S): Mus musculus (Mouse) 
2023-08-30 | PXD039915 | Pride
Super-resolution imaging Intracellular ca2+ imaging Actin cytoskeleton Multiphoton microscopy Renal epithelial cell Immune complex-mediated glomerulopathy Mycophenolic acid Glomerular filtration barrier 
MetabolomicsLipid biomarkers for algal resistance to viral infection in the ocean

Marine viruses play a key role in regulating phytoplankton populations, greatly affecting the biogeochemical cycling of major nutrients in the ocean. Resistance to viral infection has been reported for various phytoplankton species under laboratory conditions. Nevertheless, the occurrence of resi...

2023-06-12 | MTBLS3323 | MetaboLights
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