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ProteomicsCompartmentalization of HP1 proteins in pluripotency acquisition and maintenance
Embryonic stem cells (ESCs) have a hyperdynamic chromatin structure characterized by fewer discrete foci of heterochromatin protein 1 family of proteins (HP1) compared to somatic cells. During reprogramming of somatic cells, depletion of HP1γ early, reduced, while depletion later, enhanced the gener...
ORGANISM(S): Mus musculus (Mouse) 
2017-12-13 | PXD006817 | Pride
Pluripotency Ipsc Hp1 Esc 
ProteomicsWhole-cell and plasma membrane proteomics of herpes simplex virus-1 infection reveals cell surface remodelling via pUL56-mediated GOPC degradation
Herpesviruses are ubiquitous in the human population and they extensively remodel the cellular environment during infection. Multiplexed quantitative proteomic analysis over the time-course of herpes simplex virus (HSV)-1 infection was used to characterize changes in the host-cell proteome and the k...
ORGANISM(S): Homo sapiens (Human) Human alphaherpesvirus 1 
2020-10-15 | PXD021351 | Pride
Quantitative proteomics Uncharacterized orf Immune evasion Membrane trafficking Virus host interaction Proteasomal degradation Herpesvirus 
UnknownService delivery challenges in HIV care during the first year of the COVID-19 pandemic: results from a site assessment survey across the global IeDEA consortium.
Not available
S-EPMC9742047 | biostudies-literature
UnknownRisk factors for COVID-19-related in-hospital mortality in a high HIV and tuberculosis prevalence setting in South Africa: a cohort study.
Not available
S-EPMC8336996 | biostudies-literature
UnknownDifference in mortality among individuals admitted to hospital with COVID-19 during the first and second waves in South Africa: a cohort study.
Not available
S-EPMC8270522 | biostudies-literature
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