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UnknownUsing the MR-Base platform to investigate risk factors and drug targets for thousands of phenotypes.
Not available
S-EPMC6694718 | biostudies-literature
UnknownThe MR-Base platform supports systematic causal inference across the human phenome.
Not available
S-EPMC5976434 | biostudies-literature
UnknownPhenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases.
Not available
S-EPMC7610464 | biostudies-literature
MetabolomicsHeadspace volatile organic compounds from bacteria implicated in ventilator-associated pneumonia analysed by TD-GC/MS
Ventilator-associated pneumonia (VAP) is a healthcare-acquired infection arising from the invasion of the lower respiratory tract by opportunistic pathogens in ventilated patients. The current method of diagnosis requires the culture of an airway sample such as bronchoalveolar lavage, which is invas...
2018-08-08 | MTBLS497 | MetaboLights
MetabolomicsCoupled Mass-Spectrometry-Based Lipidomics Machine Learning Approach for Early Detection of Clear Cell Renal Cell Carcinoma

A discovery-based lipid profiling study of serum samples from a cohort that included patients with clear cell Renal Cell Carcinoma (ccRCC) stage I, II, III, and IV (n=112) and controls (n=52) was performed using ultraperformance liquid chromatography coupled to quadrupole-time-of-flight mass spec...

2020-11-20 | MTBLS1839 | MetaboLights
MetabolomicsPostoperative Metabolic Phenoreversion in Clear Cell Renal Cell Carcinoma

The ultimate goal of surgical treatment in cancer is to remove the tumor mass for restoring a healthy state. A 16-lipid panel that discriminated healthy controls from clear cell renal cell carcinoma (ccRCC) patients in a prior study was evaluated in the present work in paired-serum samples collec...

2023-01-02 | MTBLS3838 | MetaboLights
MetabolomicsMetabolic phenotyping of urine from a dementia research cohort
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...
2022-03-01 | MTBLS719 | MetaboLights
UnknownMaintenance rituximab or observation after frontline treatment with bendamustine-rituximab for follicular lymphoma.
Not available
S-EPMC6486816 | biostudies-literature
UnknownMolecular evolution of the switch for progesterone and spironolactone from mineralocorticoid receptor agonist to antagonist.
Not available
S-EPMC6744879 | biostudies-literature
UnknownCirculating Tumor Cell Number as a Response Measure of Prolonged Survival for Metastatic Castration-Resistant Prostate Cancer: A Comparison With Prostate-Specific Antigen Across Five Randomized Phase III Clinical Trials.
Not available
S-EPMC5815402 | biostudies-literature
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