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ProteomicsWhole proteome analysis of mesonephric-derived cancers describes new potential biomarkers
Mesonephric carcinomas (ME) and Female Adnexal Tumors of probable Wolffian Origin (FATWO) are thought to derive from remnants of the Wolffian/mesonephric ducts – anlages of the male reproductive tract. Mesonephric-like carcinomas (MLC) show identical morphology to ME of the cervix, but occur in the ...
ORGANISM(S): Homo sapiens (Human) 
2020-11-02 | PXD020879 | Pride
Tmt Mesonephric 
MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
ProteomicsProteomic profiling identifies muscle-invasive bladder cancers with distinct biology and responses to platinum-based chemotherapy
Platinum-based neoadjuvant chemotherapy (NAC) prior to radical cystectomy is the preferred treatment for muscle-invasive bladder cancer (MIBC) despite modest survival benefit and significant associated toxicities. Here, we profiled the global proteome of MIBC tumours pre- and post-NAC treatment usin...
ORGANISM(S): Homo sapiens (Human) 
2025-02-11 | PXD049435 | Pride
Bladder cancer Mibc 
TranscriptomicsTranscription profiling of wild type and hog1 Candida albicans subjected to environmental stresses that are known to activate the Hog1 Stress-activated Protein Kinase
Based on studies in S. pombe (Chen et al., 2003), we predicted that conditions which activate C. albicans Hog1 would result in the induction of a common set of genes that are regulated by this SAPK (Smith et al., 2004). Hence in this study we compared the global transcriptional responses of wild-typ...
ORGANISM(S): Candida albicans 
2007-07-05 | E-MEXP-1134 | biostudies-arrayexpress
ProteomicsThe CASP3 Prodomain Regulates Human Cell Survival and Proliferation
CASPASE-3 (CASP3) is well known for its proteolytic function that mediates multiple key cell death-initiated processes and other related cellular processes. However, the possibility that CASP3 may also possess important additional non-catalytic functions in mammalian cells has remained largely unexp...
ORGANISM(S): Homo sapiens (Human) 
2024-01-17 | PXD045234 | Pride
Casp3 Mammary cells 
UnknownAssessing endgame strategies for the elimination of lymphatic filariasis: A model-based evaluation of the impact of DEC-medicated salt.
Not available
S-EPMC5547057 | biostudies-literature
TranscriptomicsTranscription profiling of synectin knock-out mouse primary endothelial cells before and after FGF2 induction
Transcriptional regulatory effects of synectin deletion in murine primary endothelial cells both before and after FGF2 induction.
ORGANISM(S): Mus musculus 
2006-10-01 | E-MEXP-820 | biostudies-arrayexpress
UnknownEvaluating elimination thresholds and stopping criteria for interventions against the vector-borne macroparasitic disease, lymphatic filariasis, using mathematical modelling.
Not available
S-EPMC9971242 | biostudies-literature
TranscriptomicsTranscription profiling of EhV-86 Infection of E. huxleyi 1516
Not available
ORGANISM(S): Emiliania huxleyi 
2013-01-30 | E-MAXD-8 | biostudies-arrayexpress
TranscriptomicsThe Fusarium graminearum Histone H3 K27 Methyltransferase KMT6 Regulates Development and Expression of Secondary Metabolite Gene Clusters
We performed ChIP-seq of histone modifications and RNA-seq in WT and kmt6 mutant Fusarium graminearum grown in high and low nitrogen conditions. Two replicates of RNA seq for WT and kmt6 strains at high and low nitrogen. Four histone modification ChIPs in WT and kmt6 mutant strains at high and low n...
ORGANISM(S): Fusarium graminearum 
2014-02-27 | E-GEOD-50689 | biostudies-arrayexpress
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