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ProteomicsSchwann cell condition medium MS
The effects of Schwann cells on the neuro-stroma niche in pancreatic ductal adenocarcinoma (PDAC) remain to be explored. Here, single-cell RNA-sequencing and spatial transcriptome analysis of PDAC tissues reveals that Schwann cells induce malignant subtypes of tumour cells and cancer-associated fibr...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2023-06-27 | PXD042556 | Pride
Rsc96 Cm Snf96.2 
UnknownPancreatic cancer extracellular vesicles stimulate Schwann cell activation and perineural invasion in vitro via IL-8/CCL2.
Not available
S-EPMC11950487 | biostudies-literature
UnknownTranilast inhibits the expression of genes related to epithelial-mesenchymal transition and angiogenesis in neurofibromin-deficient cells.
Not available
S-EPMC5904101 | biostudies-literature
UnknownMutation of PTPN11 (Encoding SHP-2) Promotes MEK Activation and Malignant Progression in Neurofibromin-Deficient Cells in a Manner Sensitive to BRAP Mutation.
Not available
S-EPMC9140047 | biostudies-literature
UnknownMicroRNA profiling of peripheral nerve sheath tumours identifies miR-29c as a tumour suppressor gene involved in tumour progression.
Not available
S-EPMC3590650 | biostudies-literature
ProteomicsTCTP-interacting proteins in normal and tumor Schwann cells
Comparison of TCTP-interacting proteins in between sNF96.2 MPNST cells (NF1-associated malignant tumor cells) and human Schwann cells
ORGANISM(S): Homo Sapiens (human) 
2018-11-05 | PXD010662 | JPOST Repository
ProteomicsSWATH-MS in EF1A1- and EF1A2-deficient Schwann and MPNST cells
The proteins expressed in normal human Schwann and sNF96.2 MPNST cells treated with EF1A1- and EF1A2-siRNA were profiled by SWATH-MS.
ORGANISM(S): Homo Sapiens (human) 
2018-11-05 | PXD007603 | JPOST Repository
UnknownSNAIL Transctiption factor in prostate cancer cells promotes neurite outgrowth.
Not available
S-EPMC8253511 | biostudies-literature
ProteomicsSWATH-MS in TCTP-deficient MPNST cells
EF1A2-binding proteins in TCTP-deficient MPNST cells were identified by immuno-precipitation using anti-FLAG antibody and SWATH. To verify whether the change of the amount of EF1A2-binding proteins caused the cellular expression change, the proteins expressed in sNF96.2 MPNST cells treated with TCTP...
ORGANISM(S): Homo Sapiens (human) 
2018-11-05 | PXD007606 | JPOST Repository
GenomicsTSPO deficiency promotes the progression of malignant peripheral sheath tumors by regulating the G2/M phase of the cell cycle via CDK1
TSPO deficiency promotes the progression of malignant peripheral sheath tumors by regulating the G2/M phase of the cell cycle via CDK1
PRJNA1128681 | ENA
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