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GenomicsRif1 Prevents Resection of DNA Breaks and Promotes Immunoglobulin Class Switching
DNA double-strand breaks (DSBs) represent a threat to the genome because they can lead to loss of genetic information and chromosome rearrangements. The DNA repair protein p53 binding protein 1 (53BP1) protects the genome by limiting nucleolytic processing of DSBs by a mechanism that requires its ph...
ORGANISM(S): Mus musculus 
2013-03-01 | E-GEOD-42298 | biostudies-arrayexpress
UnknownAuditory and cognitive effects of aging on perception of environmental sounds in natural auditory scenes.
Not available
S-EPMC3839956 | biostudies-literature
UnknownCourse and Predictors of Cognitive Function in Patients With Prostate Cancer Receiving Androgen-Deprivation Therapy: A Controlled Comparison.
Not available
S-EPMC4461804 | biostudies-literature
TranscriptomicsTranscription profiling of Bacillus anthracis over 8 hours covering the entire life cycle
This is a series of expression measurements done during an 8 hour time course of B. anthracis growth in modified G medium. This time frame includes an entire life cycle.
ORGANISM(S): Bacillus anthracis 
2006-09-01 | E-MEXP-788 | biostudies-arrayexpress
UnknownVentilatory threshold may be a more specific measure of aerobic capacity than peak oxygen consumption rate in persons with stroke.
Not available
S-EPMC5588902 | biostudies-literature
Transcriptomicsc3h10t1/2 with dexamethasone
determine genes regulated by dexamethasone in c3h10t1/2 cells after 90 minutes of treatment compared to vehicle Keywords: treatment comparison microarray c3h10t1/2 cells were treated with vehicle or 1uM dexamethasone for 90 minutes (3 biological replicates of each) RNA samples were isolated from RNe...
ORGANISM(S): Mus musculus 
2010-05-25 | E-GEOD-10900 | biostudies-arrayexpress
TranscriptomicsRate of elongation by RNA polymerase II is influenced by specific gene features and histone modifications
The rate of transcription elongation plays important roles in the timing of expression of full-length transcripts as well as for the regulation of alternative splicing. In this study we coupled Bru-Seq technology with 5,6-dichlorobenzimidazole 1-M-NM-2-D-ribofuranoside (DRB) to estimate the elongati...
ORGANISM(S): Homo sapiens 
2014-04-01 | E-GEOD-55534 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse nmyc misexpression in lung (gain of function)
Understanding how lung progenitor cells balance; proliferation against differentiation is relevant to clinical; disorders such as bronchopulmonary dysplasia of; premature babies and lung cancer. Previous studies have; established that lung development is severely disrupted in; mouse mutants with red...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-6077 | biostudies-arrayexpress
TranscriptomicsmRNA composition of IRP1 mRNPs in mouse tissues
Affymetrix microarrays were used to determine the mRNA composition of mRNPs obtained by immunoprecipitation with IRP1 (iron regulatory protein 1). Reference Sanchez at al., 2007 Nat. Protoc. Affymetrix microarrays were used to determine the mRNA composition of mRNPs obtained by immunoprecipitation ...
ORGANISM(S): Mus musculus 
2011-12-09 | E-GEOD-17096 | biostudies-arrayexpress
TranscriptomicsmRNA composition of IRP2 mRNPs in mouse tissues
Affymetrix microarrays were used to determine the mRNA composition of mRNPs obtained by immunoprecipitation with IRP2 (iron regulatory protein 2). Reference Sanchez at al., 2007 Nat. Protoc. Affymetrix microarrays were used to determine the mRNA composition of mRNPs obtained by immunoprecipitation ...
ORGANISM(S): Mus musculus 
2011-12-09 | E-GEOD-17097 | biostudies-arrayexpress
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