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TranscriptomicsExpression data from human skin exposed to solar-simulated radiation with or without sunscreen
Despite widespread use of sunscreens that minimize erythema by blocking ultraviolet B (UVB) radiation, incidence rates of melanoma continue to rise. In considering this disparity between intervention and disease prevalence, we investigated the in vivo transcriptome of human skin treated with sunscr...
ORGANISM(S): Homo sapiens 
2011-10-18 | E-GEOD-22083 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae FHL1 and IFH1 mutants
Affymetrix experiment performed on RNA isolated from Wild type, FHL1 deleted and FHL1,IFH1 double deleted strains. Data aquired in duplicate.,In S. cerevisiae the mRNAs from the 138 ribosomal protein (RP) genes are amongst the most abundant in the cell, and their transcription is regulated tightly s...
ORGANISM(S): Saccharomyces cerevisiae 
2007-07-07 | E-GEOD-2096 | biostudies-arrayexpress
GenomicsAuthentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1
Whole genome sequencing (WGS) from snap-frozen oesophageal tumour tissue and germline nucleic acids isolated from peripheral blood mononuclear cells (PBMC) was performed as part of the International Cancer Genome Consortium project and OCCAMS consortium (1,2). Filtered read sequences were mapped to ...
ORGANISM(S): Homo sapiens 
2016-09-09 | E-MTAB-4600 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse total pancreatic RNA from 3 week old NOD.scid, NOD, BDC2.5/NOD and BDC2.5/NOD.scid animals
Total pancreatic RNA was isolated from 3 week old NOD.scid, NOD, BDC2.5/NOD and BDC2.5/NOD.scid animals by GITC method. Targets were produced using standard Affymetrix procedures from about 10ug total RNA. The data from NOD.scid, NOD, BDC2.5/NOD and BDC2.5/NOD.scid Affymetrix MGU74Av2 cel files was ...
ORGANISM(S): Mus musculus 
2007-10-12 | E-GEOD-1623 | biostudies-arrayexpress
ModelsOrtega2013 - Interplay between secretases determines biphasic amyloid-beta level
Ortega2013 - Interplay between secretases determines biphasic amyloid-beta level This model is described in the article: Interplay between ?-, ?-, and ?-secretases determines biphasic amyloid-? protein level in the presence of a ?-secretase inhibitor. Ortega F, Stott J, Visser...
2024-09-02 | BIOMD0000000556 | BioModels
ProteomicsROR2 drives right ventricular heart failure via disruption of proteostasis
This study assessed the impact of ROR2 expression on the global proteome using neonatal rat ventricular myocytes (NRVMs) using adenovirus to overexpress ROR2 vs control NRVMs with and without MG132 to block the proteasome to characterize proteasome-mediated clearance.
ORGANISM(S): Rattus norvegicus (Rat) 
2026-04-28 | PXD056556 | Pride
Proteostasis Ror2 Cardiomyocyte 
MetabolomicsIntegrating genomics and multi‐platform metabolomics enables metabolite QTL detection in breeding‐relevant apple germplasm
Apple (Malus × domestica) has commercial and nutritional value, but breeding constraints of tree crops limit varietal improvement. Marker-assisted selection minimizes these drawbacks, but breeders lack applications for targeting fruit phytochemicals. To understand genotype-phytochemical associations...
2021-09-21 | MTBLS2327 | MetaboLights
ProteomicsSo_Kinase_Networks_in_TRAIL_induced_apoptosis
This submission consists of the mass spectrometry raw files for the manuscript by So et al. (Kinase Networks in TRAIL induced apoptosis). This submission contains files for the data presented as supplementary tables 5 (interaction network of 104 protein kinases in DLD-1 cells) acquired on a QSTAR E...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-01-09 | MSV000078989 | MassIVE
TranscriptomicsTranscription profiling of Bos taurus testis 2, 4 and 8 weeks, time series
Bene expression profile of Angus bovine testis tissue at 2, 4 and 8 weeks of age using Affymetrix Bovine GeneChip Experiment Overall Design: Samples obtained from Angus bull calves at 2, 4 and 8 weeks of age. Two replicates at each age, 6 total samples.
ORGANISM(S): Bos taurus 
2008-11-06 | E-GEOD-5970 | biostudies-arrayexpress
MetabolomicsPTER is an N-acetyltaurine hydrolase that regulates feeding and obesity

Taurine is a conditionally essential micronutrient and one of the most abundant amino acids in humans1-3. In endogenous taurine metabolism, dedicated enzymes are involved in biosynthesis of taurine from cysteine as well as the downstream metabolism of secondary taurine metabolites4,5. One such ta...

2024-09-11 | MTBLS10408 | MetaboLights
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