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TranscriptomicsTranscription profiling of mouse macrophages infected with B. melitensis
Facultative intracellular Brucella infect and survive inside macrophages, and the outcome of macrophage-Brucella interaction is a basis for establishment of a chronic Brucella infection. The majority of Brucella are killed at the early infection stage. A subpopulation of virulent Brucella strains is...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-5202 | biostudies-arrayexpress
TranscriptomicsGene expression associated with liver metabolism during viral hemorrhagic fever
Rhesus macaques (Macaca mulatta) infected with a lethal dose of lymphocytic choriomeningitis virus-strain WE (LCMV-WE) provide a model for Lassa fever virus infection of man. Like Lassa fever in human beings, disease begins with flu-like symptoms but can progress to morbidity fairly rapidly. Previ...
ORGANISM(S): Macaca mulatta 
2010-06-16 | E-GEOD-12254 | biostudies-arrayexpress
TranscriptomicsThe immunoregulatory effect of macrophage-specific PPAR gamma deficiency on experimental inflammatory bowel disease
Inflammatory bowel disease (IBD) is a condition characterized by severe intestinal inflammation and immune cell activation. The severity of the disease can be mitigated by compounds which activate peroxisome proliferator-activated receptor gamma (PPAR gamma), a receptor present widely in tissues in...
ORGANISM(S): Mus musculus 
2011-11-12 | E-GEOD-23421 | biostudies-arrayexpress
TranscriptomicsCharacterization of an Entamoeba histolytica High-Mobility-Group Box Protein Induced during Intestinal Infection
The unicellular eukaryote Entamoeba histolytica is a human parasite that causes amebic dysentery and liver abscess. A genome-wide analysis of gene expression modulated by intestinal colonization and invasion identified an up-regulated transcript that encoded a putative high-mobility-group box (HMGB)...
ORGANISM(S): Entamoeba histolytica 
2008-11-19 | E-GEOD-12204 | biostudies-arrayexpress
TranscriptomicsTargets of the E. histolytica transcription factor URE3-BP
The E. histolytica transcription factor URE3-BP is a calcium-responsive regulator of two E. histolytica virulence genes, hgl5 and fdx1. URE3-BP was previously identified by a yeast one-hybrid screen of E. histolytica proteins capable of binding to the sequence TATTCTATT (URE3) in the promoter region...
ORGANISM(S): Entamoeba histolytica 
2008-10-14 | E-GEOD-12188 | biostudies-arrayexpress
TranscriptomicsMembers of the Entamoeba histolytica transmembrane kinase family play non-redundant roles in growth and phagocytosis
Entamoeba histolytica contains a large and novel family of transmembrane kinases (TMK) with proposed roles that include both amebic response to the environment and immune evasion. In the later case, the process requires several elements --these include a large gene family encoding antigenically dist...
ORGANISM(S): Entamoeba histolytica 
2010-11-01 | E-GEOD-19064 | biostudies-arrayexpress
UnknownStandardized metadata for human pathogen/vector genomic sequences.
Not available
S-EPMC4061050 | biostudies-literature
UnknownKetamine, Etomidate, and Mortality in Emergency Department Intubations.
Not available
S-EPMC12706683 | biostudies-literature
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