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ProteomicsRPA70 interactors in BJ and BJ RAS
Activation of oncogenes in healthy cells leads to a permanent cell cycle arrest termed oncogene-induced senescence (OIS) characterized by increased DNA damage and deep epigenetic resetting. Bypassing this premalignant state promotes tumorigenesis. Here, we show that cells entering OIS accumulate hig...
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD060652 | Pride
Senescence Rpa70 Rnaseh1 R-loop 
UnknownA novel TGFβ modulator that uncouples R-Smad/I-Smad-mediated negative feedback from R-Smad/ligand-driven positive feedback.
Not available
S-EPMC4321984 | biostudies-literature
UnknownHarmful R-loops are prevented via different cell cycle-specific mechanisms.
Not available
S-EPMC8298424 | biostudies-literature
UnknownHead-to-head antisense transcription and R-loop formation promotes transcriptional activation.
Not available
S-EPMC4426458 | biostudies-literature
UnknownAn essential gene screening identifies yeast Mot1 as a suppressor of R-loops and genome instability.
Not available
S-EPMC12912698 | biostudies-literature
UnknownAttenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis.
Not available
S-EPMC5490191 | biostudies-literature
Unknownr3Cseq: an R/Bioconductor package for the discovery of long-range genomic interactions from chromosome conformation capture and next-generation sequencing data.
Not available
S-EPMC3711450 | biostudies-literature
UnknownDopamine D(2) receptor-mediated modulation of adenosine A(2A) receptor agonist binding within the A(2A)R/D(2)R oligomer framework.
Not available
S-EPMC3705641 | biostudies-literature
TranscriptomicsMolecular classification of mature aggressive B cell lymphoma using digital multiplexed gene expression on formalin-fixed paraffin-embedded biopsy specimens [FFPE]
The most frequent mature aggressive B-cell lymphomas are diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma (BL). Patients suffering from molecularly defined BL (mBL) but treated with a regimen developed for DLBCL show an unfavorable outcome compared to mBL treated with chemotherapy regimens...
ORGANISM(S): Homo sapiens 
2013-09-25 | E-GEOD-48182 | biostudies-arrayexpress
TranscriptomicsMolecular classification of mature aggressive B cell lymphoma using digital multiplexed gene expression on formalin-fixed paraffin-embedded biopsy specimens [Frozen tissue]
The most frequent mature aggressive B-cell lymphomas are diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma (BL). Patients suffering from molecularly defined BL (mBL) but treated with a regimen developed for DLBCL show an unfavorable outcome compared to mBL treated with chemotherapy regimens...
ORGANISM(S): Homo sapiens 
2013-09-25 | E-GEOD-48183 | biostudies-arrayexpress
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