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ProteomicsSoluble VCAM-1 may serve as a pharmacodynamic CSF marker to monitor BACE2 activity in non-human primates
The beta-secretase beta-site APP cleaving enzyme 1 (BACE1) is a major drug target for Alzheimer’s disease (AD). Clinically tested BACE1 inhibitors induced unexpected cognitive side effects that may stem from their cross-inhibition of the homologous protease BACE2. Yet, little is known about BACE2 fu...
ORGANISM(S): Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) 
2025-07-16 | PXD056159 | Pride
Dia Cerebrospinal fluid Alzheimer's disease Csf Bace1 Macaca fascicularis Labelfree Vcam1 
UnknownEctopic Tumor VCAM-1 Expression in Cancer Metastasis and Therapy Resistance.
Not available
S-EPMC9735769 | biostudies-literature
UnknownIncreased PRR14 and VCAM-1 level in serum of patients with Parkinson's disease.
Not available
S-EPMC9561935 | biostudies-literature
UnknownMesothelium expression of vascular cell adhesion molecule-1 (VCAM-1) is associated with an unfavorable prognosis in epithelial ovarian cancer (EOC).
Not available
S-EPMC5341143 | biostudies-literature
UnknownSoluble VCAM-1 May Serve as a Pharmacodynamic CSF Marker to Monitor BACE2 Activity in Non-Human Primates.
Not available
S-EPMC12280488 | biostudies-literature
UnknownCardiac fibroblast-derived VCAM-1 enhances cardiomyocyte proliferation for fabrication of bioengineered cardiac tissue.
Not available
S-EPMC6581822 | biostudies-literature
TranscriptomicsInhibition of VCAM-1 expression by CORM-3: the role of the ubiquitin proteasome system, p38 and mitochondrial respiration
Carbon monoxide (CO) abrogates TNF-alpha mediated inflammatory responses in endothelial cells, yet, the underlying mechanism hereof is still elusive. We sought to explore potential mechanisms by which CO down-regulates VCAM-1 expression on TNF-alpha stimulated human umbilical vein endothelial cells ...
ORGANISM(S): Homo sapiens 
2011-07-11 | E-GEOD-22175 | biostudies-arrayexpress
UnknownHuman IL-8 regulates smooth muscle cell VCAM-1 expression in response to endothelial cells exposed to atheroprone flow.
Not available
S-EPMC2719853 | biostudies-literature
UnknownVEGF-A isoforms differentially regulate ATF-2-dependent VCAM-1 gene expression and endothelial-leukocyte interactions.
Not available
S-EPMC4142621 | biostudies-literature
UnknownPreoperative soluble VCAM-1 contributes to predict late mortality after coronary artery surgery.
Not available
S-EPMC7661653 | biostudies-literature
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