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TranscriptomicsTranscription profiling of mouse livers from animals fed four different diets
Beyond the DNA sequence difference between humans and closely related apes, there are large differences in the environments that these species experience. One prominent example for this is diet. The human diet diverges from those of other primates in various aspects, such as having a high calorie an...
ORGANISM(S): Mus musculus 
2009-04-08 | E-GEOD-6297 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of brains of mice fed four different diets for a 2-week duration
Beyond the DNA sequence difference between humans and closely related apes, there are large differences in the environments that these species experience. One prominent example for this is diet. The human diet diverges from those of other primates in various aspects, such as having a high calorie an...
ORGANISM(S): Mus musculus 
2009-09-23 | E-GEOD-6285 | biostudies-arrayexpress
TranscriptomicsGene expression data from adult postnatal cerebellum, prefrontal cortex and liver: comparison on tissue differences
To understand the roles of molecules in functional differentiation among adult human tissues, we performed a systematic survey of mRNA, protein, and protein phosphorylation as well as miRNA expression, in three tissues: cerebellum, prefrontal cortex and liver. We found that tissues were clearly dist...
ORGANISM(S): Homo sapiens 
2013-01-04 | E-GEOD-19504 | biostudies-arrayexpress
TranscriptomicsIdentification of response genes upon neuronal activation in mouse cortical neurons
We search for developmental changes specific to humans by examining gene expression profiles in the human, chimpanzee and rhesus macaque prefrontal and cerebellar cortex. In both brain regions, developmental patterns were more evolved in humans than in chimpanzees. The major human specific genes in ...
ORGANISM(S): Mus musculus 
2012-02-02 | E-GEOD-29139 | biostudies-arrayexpress
TranscriptomicsThe mRNA expression patterns in macaque brains from prenatal to neonatal
We search for developmental changes specific to humans by examining gene expression profiles in the human, chimpanzee and rhesus macaque prefrontal and cerebellar cortex. In both brain regions, developmental patterns were more evolved in humans than in chimpanzees. To distinguish whether the human s...
ORGANISM(S): Macaca mulatta 
2012-02-02 | E-GEOD-29138 | biostudies-arrayexpress
TranscriptomicsGene expression data from mouse postnatal brain development
In development, timing is of the utmost importance, and the timing of various developmental processes are often changed during evolution. We measured the timing of gene expression changes in the brains of two species of mice throughout postnatal development. Mus musculus and Mus spretus mice were br...
ORGANISM(S): Mus musculus 
2009-03-09 | E-GEOD-11528 | biostudies-arrayexpress
TranscriptomicsGene expression data from primate postnatal brain development - superior frontal gyrus
In development, timing is of the utmost importance, and the timing of various developmental processes are often changed during evolution. During human evolution sexual maturation has been delayed relative to other primates and this may have played a critical role for both the increase of human brain...
ORGANISM(S): Homo sapiens 
2009-03-09 | E-GEOD-15163 | biostudies-arrayexpress
TranscriptomicsGene expression changes during primate postnatal brain development
In development, timing is of the utmost importance, and the timing of various developmental processes are often changed during evolution. During human evolution sexual maturation has been delayed relative to other primates and this may have played a critical role for both the increase of human brain...
ORGANISM(S): Macaca mulatta 
2009-03-09 | E-GEOD-11512 | biostudies-arrayexpress
TranscriptomicsComparison of expression profiles of once and three time linearly amplified samples
In order to assess the impact of three rounds of linear amplification on the technical reproducibility of gene expression measurements, we performed twelve microarray experiments. We analysed mouse RNA from cortex, cerebellum and liver from one individual. One RNA sample of 5µg from each of the thr...
ORGANISM(S): Mus musculus 
2010-06-08 | E-GEOD-21389 | biostudies-arrayexpress
TranscriptomicsWidespread splicing changes in human brain development and aging
Differences in transcript splicing are well documented among tissues and between sexes in humans and other organisms. Further, splicing changes in selected genes have been reported in human and mouse brain development. Using high-throughput RNA sequencing we characterized the transcriptome-wide spli...
ORGANISM(S): Homo sapiens 
2013-01-22 | E-GEOD-26586 | biostudies-arrayexpress
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