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We determined which metabolic pathways are activated by hypoxia-inducible factor 1-mediated (HIF-1-mediated) protection against oxygen-induced retinopathy (OIR) in newborn mice, the experimental correlate to retinopathy of prematurity, a leading cause of infant blindness. HIF-1 coordinates the chang...
2019-07-05 | MTBLS856 | MetaboLights
FOXA1 is a FKHD family protein that translates epigenetic signatures at target enhancers to lineage-specific transcription and differentiation. Through genome-wide location analyses, here we show that FOXA1 expression and occupancy are, in turn, required for the maintenance of this epigenetic signat...
ORGANISM(S): Homo sapiens 
Despite having exquisite control over nanoparticle design, controlling nanoparticle fate in vivo remains a major barrier for clinical translation. This is because we do not understand how nanoparticles interact with the surrounding environment in vivo and how this lack of control contributes towards...
ORGANISM(S): Mus musculus (Mouse) 
2024-09-14 | PXD011354 | Pride
The Antibiotic Resistant Sepsis Pathogens Framework Initiative aims to develop a framework dataset of 5 sepsis pathogens (5 strains each) using an integrated application of genomic, transcriptomic, metabolomic and proteomic technologies. The pathogens included in this initiative are: Escherichia col...
ORGANISM(S): Klebsiella variicola Homo sapiens (Human) Klebsiella pneumoniae 
2021-07-05 | PXD016672 | Pride
Immature (19/20 days of age) Alpk:APfCD-1 mice were treated with arachis oil (AO) vehicle or 0.4mg/kg 17beta-estradiol (E2), via a single subcutaneous injection, and sacrificed at 1hr, 2hr, 4hr, 8hr, 24hr, 48hr, 72hr post dose.
ORGANISM(S): Mus musculus 
OSMAC guided bioprospecting of Atlantic sponges reveals novel bacterial species and evidence for the antimicrobial thiazole alkaloid agrochelin II A tandem mass spec data file from the crude extract of Stappia 28M-7 Taxonomy ID: 2762596
ORGANISM(S): Stappia (ncbitaxon:152161) 
2025-08-11 | MSV000098784 | MassIVE
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-08-28 | MSV000084248 | MassIVE
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